Results 111 to 120 of about 17,437 (131)

Glial changes and gene expression in Alzheimer's disease from snRNA-Seq and spatial transcriptomics

Journal of Alzheimer’s Disease
Background Alzheimer's disease (AD) is characterized by cortical atrophy, glutamatergic neuron loss, and cognitive decline. However, large-scale quantitative assessments of cellular changes during AD pathology remain scarce.
Songren Wei, Chenyang Li, Wenxuan Li, Fumiao Yuan, Jingjing Kong, Xi Su, Peng Huang, Hongbo Guo, Jiangping Xu, Haitao Sun   +9 more
openaire   +2 more sources

snRNA-seq of Dugesia:Brain

snRNA-seq of Dugesia ...
openaire   +1 more source

Integrative GWAS and snRNA-seq Reveal a Mesenchymal-Like Endothelial Signature in Moyamoya Disease

Stroke
BACKGROUND: Moyamoya disease (MMD) has a strong genetic basis, with the rare RNF213 p.Arg4810Lys variant (rs112735431) representing a major risk factor, while the broader genetic architecture and disease-relevant vascular cell types remain ...
Yudai Hirano, Satoru Miyawaki, Kyuto Sonehara, Shinichi Namba, Hirotaka Inoue, Yuya Shirai, Hideaki Imai, Hiroki Hongo, Masahiro Shimizu, Hideaki Ono, Yumie Mizoro, Koichi Matsuda, Shotaro Ogawa, Seiei Torazawa, Yu Sakai, Daisuke Sato, Takahiro Tsuchiya, So Hirata, Satoshi Koizumi, Shogo Dofuku, Yuki Shinya, Satoshi Kiyofuji, Daisuke Komura, Akira Teraoka, Hirofumi Nakatomi, Shumpei Ishikawa, Yukinori Okada, Nobuhito Saito   +27 more
openaire   +2 more sources

snRNA-seq of the cochlear nucleus

The molecular mechanisms underlying the complex functions of the cochlear nucleus (CN) remain poorly understood, requiring a thorough characterization of cellular properties. We utilized single-nuclei RNA sequencing (snRNA-seq) and spatial enhanced resolution omics-sequencing (Stereo-seq) to generate a comprehensive celluar and molecular atlas of the ...
openaire   +1 more source

Abstract 6840: Automated preparation of single nuclei from FFPE samples for snRNA-Seq

Cancer Research
Abstract S2 Genomics developed the Singulator™ 100 and 200 Systems to automate the processing of fresh, frozen, or OCT tissues into single cell or single nuclei suspensions using disposable cartridges, reagents, and customizable protocols.
Stevan Jovanovich, Nate Pereira, Danielle Meyer, Catherine Snopkowski, Ignas Masilionis, Brigita Meškauskaitė, Meril Takizawa, Zaki Abou-Mrad, Kenny Yu, Viviane Tabar, Kathleen Luckett, Karuna Ganesh, Nabiha Khan, Ronan Chaligne   +13 more
openaire   +1 more source

An optimized FACS-free single-nucleus RNA sequencing (snRNA-seq) method for plant science research

Plant Science, 2023
Sunil Kumar Sahu
exaly  

SnRNA-Seq analysis reveals ten hub genes associated with alveolar epithelial cell injury during pulmonary acute respiratory distress syndrome

Heliyon, 2023
Yongpeng Xie, Haoran Chen
exaly  

snRNA-seq data from cochlear nucleus derive from 5 mice

The molecular mechanisms underlying the complex functions of the cochlear nucleus (CN) remain poorly understood, requiring a thorough characterization of cellular properties. We utilized single-nuclei RNA sequencing (snRNA-seq) and spatial enhanced resolution omics-sequencing (Stereo-seq) to generate a comprehensive celluar and molecular atlas of the ...
openaire   +1 more source

Human Cerebellum Atlas snRNA-seq and scQTL scripts

snRNA-seq script bundle for Human Cerebellum scQTL atlas. Linked to snRNA-seq data found on SRA (PRJNA1120369). 
openaire   +1 more source

Single-Nucleus RNA-Seq: Open the Era of Great Navigation for FFPE Tissue

International Journal of Molecular Sciences, 2023
Qinyu Ge, Xiangwei Zhao, Yunxia Guo
exaly