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Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions
Cell, 1987The RNA8 gene of Saccharomyces cerevisiae encodes an unusually large (260 kd) protein required for pre-mRNA splicing. Immunological procedures have been used to demonstrate that the RNA8 protein is in stable association with the small nuclear RNAs snR7L and snR7S, which are also known to be required for splicing and which are present in spliceosomal ...
M, Lossky +3 more
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Structure-function in Xenopus snRNPs
Molecular Biology Reports, 1990For this analysis an in vivo assay in Xenopus oocytes is being used which is based on the principle that, using site directed hydrolysis by RNAse H, a specific snRNA population can be destroyed by nuclear injection of an oligodeoxynucleotide, complementary to a part of an snRNA sequence (Pan and Prives, 1988).
Vankan P, Hamm J, Dathan NA, Mattaj IW
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Immunoelectron microscopic localization of snRNPs
Biology of the Cell, 1984Small nuclear ribonucleoprotein particles (snRNPs) were identified in nuclear sonicates of Novikoff hepatoma ascites cells and in intact Novikoff hepatoma and PtK2 cells by immunofluorescence and immunoelectron microscopy. Auto‐antibodies (anti‐Sm and anti‐RNP) obtained from patients with systemic lupus erythematosus an autoimmune disease, were used to
D L, Spector, W H, Schrier, H, Busch
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