Results 171 to 180 of about 13,335 (199)
Some of the next articles are maybe not open access.
Non-snRNP protein splicing factors
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1993III. Protein motifs in non-snRNP splicing factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 A. The RRM (RBD-CS) motif . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 B. The SR motif . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lamm, Gábor M., Lamond, Angus I.
openaire +3 more sources
SnRNAs, SnRNPs, and RNA Processing
Annual Review of Biochemistry, 1982PERSPECTIVES AND SUMMARY . SMALL RNAs . Historical Aspects . Conservation Through Evolution . Synthesis 0/ Small RNAs ..
H, Busch +3 more
openaire +2 more sources
Redistribution of U-snRNPs during mitosis
Experimental Cell Research, 1986In this study we examined the distribution of U-snRNPs during mitosis using a monoclonal antibody which recognizes the 28 kD protein associated with U-snRNP particles. During interphase U-snRNPs are concentrated within discrete intranuclear protein clusters.
D L, Spector, H C, Smith
openaire +2 more sources
snRNP proteins in health and disease
Seminars in Cell & Developmental Biology, 2018Split gene architecture of most human genes requires removal of intervening sequences by mRNA splicing that occurs on large multiprotein complexes called spliceosomes. Mutations compromising several spliceosomal components have been recorded in degenerative syndromes and haematological neoplasia, thereby highlighting the importance of accurate splicing
Michaela, Krausová, David, Staněk
openaire +2 more sources
Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly
Cell, 1990HeLa cell nuclear splicing extracts have been prepared that are specifically and efficiently depleted of U1, U2, or U4/U6 snRNPs by antisense affinity chromatography using biotinylated 2'-OMe RNA oligonucleotides. Removal of each snRNP particle prevents pre-mRNA splicing but arrests spliceosome formation at different stages of assembly. Mixing extracts
Barabino, Silvia M.L. +4 more
openaire +3 more sources
The Journal of Biochemistry, 1986
An attempt was made to immunochemically and biochemically purify and characterize the U1-snRNP(s) of mouse embryonal carcinoma cells. The results obtained by RNA analysis of U1-snRNP(s) purified immunochemically from embryoid bodies, F9 cells and PYS-2 cells indicated that the U1-snRNP(s) in these cells consisted of U1a-snRNP and U1b-snRNP.
M, Matsuda, T, Nomura, T, Kameyama
openaire +2 more sources
An attempt was made to immunochemically and biochemically purify and characterize the U1-snRNP(s) of mouse embryonal carcinoma cells. The results obtained by RNA analysis of U1-snRNP(s) purified immunochemically from embryoid bodies, F9 cells and PYS-2 cells indicated that the U1-snRNP(s) in these cells consisted of U1a-snRNP and U1b-snRNP.
M, Matsuda, T, Nomura, T, Kameyama
openaire +2 more sources
1997
Abstract In contrast to self-splicing RNA molecules which contain extensive, highly con¬ served structural elements sufficient for intron excision and exon ligation, nuclear pre-mRNA molecules possess short, conserved sequences which are limited to the 5’ and 3’ splice site and branchpoint regions (see Chapters 1, 4, and 8).
Cindy l. Will, reinhard lÜhrmann
openaire +1 more source
Abstract In contrast to self-splicing RNA molecules which contain extensive, highly con¬ served structural elements sufficient for intron excision and exon ligation, nuclear pre-mRNA molecules possess short, conserved sequences which are limited to the 5’ and 3’ splice site and branchpoint regions (see Chapters 1, 4, and 8).
Cindy l. Will, reinhard lÜhrmann
openaire +1 more source
1985
Abstract Core snRNPs isolated under very drastic conditions contain the same subset of a few small proteins, including an Sm antigen recognized by systemic lupus erythematosus (SLE) patients, bound to an evolutionary conserved domain common to all but U6 snRNAs.
C. BRUNEL +4 more
openaire +1 more source
Abstract Core snRNPs isolated under very drastic conditions contain the same subset of a few small proteins, including an Sm antigen recognized by systemic lupus erythematosus (SLE) patients, bound to an evolutionary conserved domain common to all but U6 snRNAs.
C. BRUNEL +4 more
openaire +1 more source

