Results 81 to 90 of about 7,401,341 (346)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Communism – postcommunism continuum. The urban Romania in the 21st century

open access: yesSfera Politicii, 2013
While trying to understand the deeper meanings of the transition from communism to post communism in Romania, the study analyses the evolution of urban environment.
Tudor Pitulac
doaj  

Screening analysis and selection of emission reduction concepts for intermittent combustion aircraft engines [PDF]

open access: yes
An analysis was conducted to screen, evaluate, and select three engine exhaust emission reduction concepts from a group of 14 candidate alternatives. A comprehensive literature search was conducted to survey the emission reduction technology state-of-the-
Meyers, J. E.   +3 more
core   +1 more source

Eloquent fragments: French fiction film and globalization [PDF]

open access: yes, 2007
French (and Franco-Belgian) cinema has witnessed a return to the real since the middle of the 1990s and should thus successfully have pinned down the impact of the globalizing economy on the sociopolitical sphere.
O'Shaughnessy, M
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Library as Agent of [Re]Contextualization [PDF]

open access: yes, 2009
Paper presented at the Digital Humanities 2009 conference in College Park ...
Ammerman, Jack   +2 more
core   +1 more source

European Biometric Borders and (Im)Mobilities in West Africa: Reflections on Migrant Strategies for Border Circumvention and Subversion

open access: yesPolitics & Policy
This article argues that the European biometric ID installations and securitization practices at West African borders harm African migrants and compromise the security goals of Europe and Africa.
V. Iwuoha
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

From Patriotic Education to Militarist Indoctrination—Disciplinary Power and Silent Resistance in Russia after the Onset of the War against Ukraine

open access: yesProblems of Post-Communism
Since the beginning of Russia’s war against Ukraine, various militaristic initiatives have been implemented in Russian schools. This article examines how teachers, pupils, and parents interpret state-driven patriotism amidst the war.
Jonna Alava
semanticscholar   +1 more source

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