Results 191 to 200 of about 21,610,538 (392)
Self-rated health is influenced by socioeconomic circumstances, but related differences in its structure have received little attention. The objective of this study was to examine whether self-rated health structure differs according to socioeconomic ...
Maria Fernanda Lima-Costa +2 more
doaj
[First paragraph] Conversatons with Cuba. C. PETER RIPLEY. Athens: University of Georgia Press, 1999. xxvi + 243 pp. (Cloth US$ 24.95) Real Life in Castro's Cuba. CATHERINE MOSES. Wilmington DE: Scholarly Resources, 2000. xi + 184 pp. (Paper US$
Charles Rutheiser
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
A análise espacial de indicadores de saúde tem sido um importante instrumento na detecção de diferenciais intra-urbanos. O estudo objetivou traçar um perfil dos nascimentos em Belo Horizonte, Minas Gerais, Brasil, em 2001, analisando a presença de ...
Amélia Augusta de Lima Friche +4 more
doaj
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source

