Results 191 to 200 of about 21,610,538 (392)

Differences in self-rated health among older adults according to socioeconomic circumstances: the Bambuí Health and Aging Study

open access: yesCadernos de Saúde Pública
Self-rated health is influenced by socioeconomic circumstances, but related differences in its structure have received little attention. The objective of this study was to examine whether self-rated health structure differs according to socioeconomic ...
Maria Fernanda Lima-Costa   +2 more
doaj  

Cuba on our minds

open access: yesNWIG, 2002
[First paragraph] Conversatons with Cuba. C. PETER RIPLEY. Athens: University of Georgia Press, 1999. xxvi + 243 pp. (Cloth US$ 24.95) Real Life in Castro's Cuba. CATHERINE MOSES. Wilmington DE: Scholarly Resources, 2000. xi + 184 pp. (Paper US$
Charles Rutheiser
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Indicadores de saúde materno infantil em Belo Horizonte, Minas Gerais, Brasil, 2001: análise dos diferenciais intra-urbanos

open access: yesCadernos de Saúde Pública
A análise espacial de indicadores de saúde tem sido um importante instrumento na detecção de diferenciais intra-urbanos. O estudo objetivou traçar um perfil dos nascimentos em Belo Horizonte, Minas Gerais, Brasil, em 2001, analisando a presença de ...
Amélia Augusta de Lima Friche   +4 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Neighborhood Disadvantage, Poor Social Conditions, and Cardiovascular Disease Incidence Among African American Adults in the Jackson Heart Study.

open access: yesAmerican Journal of Public Health, 2016
Sharrelle Barber   +5 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Social Structure and Personality Under Conditions of Radical Social Change: A Comparative Study of Poland (1992) and the Ukraine (1992-1993)

open access: green, 1998
Melvin L. Kohn   +6 more
openalex   +1 more source

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