Results 101 to 110 of about 1,415,295 (314)
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Deviance and Social Control in Chinese Society [PDF]
, 1978 Amy Auerbacher Wilson +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Digital Exhibitionism The Age of Exposure
Culture Unbound: Journal of Current Cultural Research, 2010 Web 2.0 has expanded the possibilities of digital creative production by individu-als and enabled the digitalisation of private life experiences. This study analyses how social media contributes to the making of personal biographies and discusses the ...
Ana María Munar
doaj +1 more source
Self-control or social control - what determines sleep hygiene in bed-sharing couples? [PDF]
Sleep Sci, 2021 Drews HJ, Göder R, Mitkidis P.
europepmc +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Smoking-Related Social Control in Indonesian Single-Smoker Couples. [PDF]
Int J Behav Med, 2021 Ayuningtyas DA +3 more
europepmc +1 more source
Psycho-Social Effects of Home Care: Results of a Randomized Controlled Trial [PDF]
, 1976 Lowell W. Gerson, A. F. E. BERRY
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source