Results 91 to 100 of about 2,600,869 (337)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Employer and Employee Obligations in Islam: A Comparative Study with Constitutional Provisions of Pakistan

Pakistan Journal of Islamic Research, 2021
Labour market of Muslim world including Pakistan is characterized with lower level of productivity resulting from job dissatisfaction, and undisciplined work environment.
Shahzadah Fahed Qureshi, Muhammad Mudassar   +1 more
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Urban and Rural Environments and Their Implications for Older Adults’ Adaptation to Heat Waves: A Systematic Review

Land
The aim of this study is to synthesise the scientific evidence on the implications of urban and rural environments on older adults’ adaptation strategies to heatwaves. Methods: The methodology follows PRISMA guidelines, which involves a systematic search
Pablo De Gea Grela, Diego Sánchez-González, Lorena Patricia Gallardo Peralta   +2 more
doaj   +1 more source

Climate Change Impacts and Adaptation to Flow of Swat River and Glaciers in Hindu Kush Ranges, Swat District, Pakistan (2003-2013) [PDF]

International Journal of Economic and Environment Geology, 2016
This work aims at the climate change impacts and adaptation to surface flow of Swat river and glacier resources in Swat river catchments area, Hindu Kush ranges, Northwest Pakistan.
Saifullah Khan, Mahmood-Ul-Hasan
doaj  

Differences in Social Distancing May Not Explain the Decreased Likelihood of SARS-CoV-2 Infection in Smokers [PDF]

, 2023
Guillaume Airagnes, Joane Matta, Maria Melchior, Marie Zins   +3 more
openalex   +1 more source

Generalization of Clustering Agreements and Distances for Overlapping Clusters and Network Communities

, 2015
A measure of distance between two clusterings has important applications, including clustering validation and ensemble clustering. Generally, such distance measure provides navigation through the space of possible clusterings.
Rabbany, Reihaneh, Zaïane, Osmar R.
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Innovation orientation and firms’ financial performance: The moderating role of new product development

Cogent Business & Management
Previous studies on the relationship between innovation orientation and firms’ financial performance have churned out conflicting results. These contradictions motivated this study.
Justice Boateng Dankwah, Sayibu Ibrahim Nnindini, Zakari Bukari   +2 more
doaj   +1 more source

Identity and Social Distance in Friendship Formation [PDF]

We analyze a network formation model where agents belong to different communities. Both individual benefits and costs depend on direct as well as indirect connections.
de Marti, Joan, Zenou, Yves
core