Results 151 to 160 of about 15,522,800 (401)

Emergence and resilience of social networks: a general theoretical framework [PDF]

open access: yesarXiv, 2005
We introduce and study a general model of social network formation and evolution based on the concept of preferential link formation between similar nodes and increased similarity between connected nodes. The model is studied numerically and analytically for three definitions of similarity. In common with real-world social networks, we find coexistence
arxiv  

Enhancing the Effectiveness of Social Dialogue Articulation in Europe (EESDA) Project No. VS/2017/0434 Comparative policy recommendations on improving social dialogue articulation and effectiveness in Europe [PDF]

open access: yes, 2019
The history of European social dialogue dates back to the mid-1980s with the Val Duchesse social dialogue initiative by the European Commission. The aim then was to involve social partners in the internal market process.
Akgüç, Mehtap, Baiocco, Sara
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

A Theory of the Knowledge Industry [PDF]

open access: yesarXiv, 2012
This paper deals with the social production of knowledge in the exact sciences. After defining the term, exact science, it delineates the broad dynamic of its history. It, then, offers a socio-economic historical explanation of why the production of knowledge has become a major industry, if not the largest industry, in the last hundred years. The paper
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Music Recommendation System for Million Song Dataset Challenge [PDF]

open access: yesarXiv, 2012
In this paper a system that took 8th place in Million Song Dataset challenge is described. Given full listening history for 1 million of users and half of listening history for 110000 users participatints should predict the missing half. The system proposed here uses memory-based collaborative filtering approach and user-based similarity. MAP@500 score
arxiv  

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