Results 111 to 120 of about 1,025,463 (296)
Social inclusion policy: Producing justice or retribution?
, 2010 The notion of social inclusion has currently gained extraordinary credence in Australia. Policy incorporating social inclusion abounds across all discipline areas with the federal government for the first time instituting a government portfolio for this ...
Macfarlane, Kym
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Gender and Social Inclusion [PDF]
, 2009 Oxfam has worked on poverty and social exclusion in the UK since the mid-1990s, with gender as a key element in its approach. GenderWorks is a two-year project funded by the European Commission across three European Union (EU) countries (the UK, Italy ...
Bennett, Fran
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Social Work and Society, 2009 The title ‘Frontiers of Social Research’ implies a pioneering spirit, embarking upon unchartered territories. However, the most fascinating and insightful moments of this book are those which explore age-old Japanese research techniques and the potential
Kate Davis
doaj
The complex and contradictory nature of alternative education provision
Cogent EducationAlthough most students experience relative success at school, there remains a population of educationally marginalised learners within educational settings, indicating that mainstream schools are challenged to appropriately meet the diverse needs of ...
Marnie Best
doaj +1 more source
BMC Health Services Research, 2018 Background The ‘perfect’ journey through an Irish Methadone Maintenance Treatment Programme (MMTP) would have a client engage appropriately with all relevant services available to them, inclusive of psychiatry, counselling, out-reach support, nursing and
Lisa Moran +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Handbook : Social inclusion through pupils' participation (SIPP)
, 2023 The purpose of the SIPP project “Social Inclusion through Pupils’ Participation” is firstly to support teachers to develop their work with participation and social inclusion based on pupils’ perspectives and experiences of social inclusion; furthermore ...
Gravesen, David Thore, +9 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source