Results 131 to 140 of about 13,496,740 (294)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Inquiry into social inclusion and Victorians with disability [PDF]
, 2014 As people with disability continue to experience exclusion from social, economic and cultural life in Victoria, this report recommends ways forward. Chair\u27s foreword Circumstances for people with disability in Victoria have markedly improved with ...
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Inclusion and Social Justice in Teacher Education
The scholarly chapters in this edited collection come from authors undertaking social justice research within the teacher education discipline. Authors examine, explore and critique those educational practices and structures that disadvantage minority ...
Burke, Jenene +2 more
core +1 more source
National report for Ireland on strategies for social protection and social inclusion: 2008-2010. [PDF]
, 2008 Following the streamlining of the Open Method of Coordination on Social Protection and Social Inclusion, Member States are now charged with translating the common objectives into National Plans for each of the three areas of Social Inclusion, Pensions ...
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
European Assertive Outreach Federation (EAOF) conference, Hamburg 2017
, 2018 The European Assertive Outreach Federation (EAOF) brings together professional colleagues to discuss advances in community care, particularly towards those who experience severe and enduring mental health challenges and promotes the Flexible Assertive ...
Kelly, Ned +9 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Social Inclusion Forum: conference report
, 2012 The Social Inclusion Forum (SIF) was established by the government as part of the structures to monitor and evaluate Ireland’s National Action Plan for Social Inclusion (NAPinclusion) 2007- 2016.
Department of Social Protection
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A conceptual study of the factors influencing e-inclusion [PDF]
, 2011 With the advancement of the Internet and supporting Information and Communication Technologies, e-inclusion has emerged as an effective means to create opportunities for all and to further individual autonomy and capability in terms of using online ...
Almuwil, A +2 more
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