Results 121 to 130 of about 1,025,463 (296)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

EASIT : Easy Access for Social Inclusion Training

Altres ajuts: EASIT (Easy Access for Social Inclusion).
Easy Access for Social Inclusion Training (EASIT)
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A Brief Foray into Social Inclusion: What does it mean for professional health practice?

, 2017
The aim of this paper is to stimulate debate around the concept of ‘social inclusion’ in the context of working in health care. A perusal of the literature shows the terms social inclusion, social capital and social participation are often used ...
Briggs, Lynne, Harris, Paul
core  

Language Use and Social Inclusion in International Retirement Migration

, 2017
The migration of older people in search for improved quality of life has become an important form of human mobility, and popular retirement destinations are often highly multilingual settings.
Laksfoss Cardozo, Ann Elisabeth, Cardozo, Ann Elisabeth Laksfoss, Per Gustafson, Ann Elisabeth Laksfoss Cardozo, Gustafson, Per,, Laksfoss Cardozo, Ann Elisabeth,, Gustafson, Per   +6 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

19 Stories of Social Inclusion – Ireland: Stories of Belonging, Contributing and Connecting

, 2019
Irish disability policy, in line with international treaties such as the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD), aims to support people with intellectual disabilities to live included lives in their community ...
Murphy, Tomás, Feely, Michael, Inclusion Ireland, Magee, Christine, McConkey, Roy, Garcia Iriarte, Edurne, Turley, Margaret   +6 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Practising Social Inclusion

, 2016
Practising Social Inclusion, edited by Ann Taket, Beth R. Crisp, Melissa Graham, Lisa Hanna, Sophie Goldingay, & Linda Wilson, Abingdon, Routledge, 2014, 311 pp., £31.99 (paperback), ISBN ...
Dee, Mike
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source