Results 91 to 100 of about 3,834,889 (342)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Assessing communicative-pragmatic ability in telehealth: e-ABaCo in autistic individuals

open access: yesFrontiers in Psychiatry
IntroductionAutism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication. Autistic individuals who are verbally fluent, often show difficulties in pragmatic ability, i.e.
Ilaria Traetta   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Stakeholder acceptance of a robot-assisted social training scenario for autistic children compared to a tablet-computer-based approach

open access: yesScientific Reports
Recent studies indicate the potential benefits of robot-assisted therapy (RAT) for children on the autism spectrum (AS), yet acceptance among stakeholders remains unclear due to methodological shortcomings in existing research.
Jonas Frenkel   +7 more
doaj   +1 more source

Economic-Social Interaction in China [PDF]

open access: yes
This paper analyzes economic-social interaction in China in connection with the country’s change of economic system. I define an economic system in terms of a multidimensional vector of broad institutional characteristics, and I emphasize that important ...
Lindbeck, Assar
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Demand for Social Interaction [PDF]

open access: yes
In this paper social interaction is modeled as a consumer good. Social interaction may provide an externality in the form of social capital, but the primary reason that individuals engage in social interaction is that these activities directly yield ...
Henry Saffer
core  

Social Interaction and Stock Market Participation: Evidence from British Panel Data [PDF]

open access: yes, 2010
This paper uses data from the British National Child Development Study to investigate the relationship between social interaction and participation in the stock market through holding stocks and/or shares at the individual level. In accordance with
Brown, S., Taylor, K.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

"You just took the jump too slowly”

open access: yesSocial Interaction, 2019
Two online videos are used to analyse social interaction in a mountain bike crash. The first provides context and a contrasting case: we view five mountain bikers taking a large gap jump in quick succession, where it is the fact that they are closely ...
Mike Lloyd
doaj   +1 more source

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