Results 101 to 110 of about 3,898,666 (292)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Social Interaction in Tax Evasion [PDF]
We analyze the tax evasion problem with social interaction among the taxpayers. If the authority commits to a fixed auditing probability, a positive share of cheating is obtained in equilibrium.
Lipatov, Vilen
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Social interaction as a heuristic for combinatorial optimization problems
, 2010 We investigate the performance of a variant of Axelrod's model for dissemination of culture - the Adaptive Culture Heuristic (ACH) - on solving an NP-Complete optimization problem, namely, the classification of binary input patterns of size $F$ by a ...
Fontanari, Jose F.
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Economic-Social Interaction in China [PDF]
This paper analyzes economic-social interaction in China in connection with the country’s change of economic system. I define an economic system in terms of a multidimensional vector of broad institutional characteristics, and I emphasize that important ...
Assar Lindbeck
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Compassion for others and well-being: a meta-analysis
Scientific ReportsCompassion has been shown to improve well-being across multiple settings. While the link between self-compassion and well-being is well-established, findings on compassion for others have been more mixed.
M. Zhuniq, F. Winter, C. Aguilar-Raab
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Communications PsychologyPast research showed that personality traits develop less strongly after younger adulthood, though the underlying processes remain poorly understood, and personality intervention studies scarcely investigated age differences.
Gabriela Küchler +5 more
doaj +1 more source
Social Interaction and Sickness Absence [PDF]
Does the average level of sickness absence in a neighborhood affect individual sickness absence through social interaction on the neighborhood level? To answer this question, we consider evidence of local benefit-dependency cultures.
Lindbeck, Assar +2 more
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