Results 101 to 110 of about 844,246 (269)

From community diagnosis to policy dialogue: co-creating childhood obesity prevention strategies in rural and urban Portugal

Frontiers in Public Health
IntroductionPromoting healthy lifestyles from early childhood is central to balanced development and the prevention of health problems throughout life.
Tania Gaspar, Tania Gaspar, Maria Rosa Nóbrega, Fábio Botelho Guedes, Fábio Botelho Guedes, Ana Cerqueira, Ana Cerqueira, Leonor Quelhas Pinto, Miguel Telo de Arriaga   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Personality intervention affects emotional stability and extraversion similarly in older and younger adults

Communications Psychology
Past research showed that personality traits develop less strongly after younger adulthood, though the underlying processes remain poorly understood, and personality intervention studies scarcely investigated age differences.
Gabriela Küchler, Kira S. A. Borgdorf, Corina Aguilar-Raab, Wiebke Bleidorn, Jenny Wagner, Cornelia Wrzus   +5 more
doaj   +1 more source

“Every professional is a climate professional”: a framework for climate responsibility in practice

Frontiers in Education
Professionals are an important class of actors often overlooked in efforts to address climate change. Across fields such as health, law, education, the built environment, and media, they combine specialised knowledge, institutional authority, and public ...
Aaron Thierry, Mario Veen
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Sleep and light ecologies of parents with young infants: descriptive findings from the SUNSHINE project

npj Biological Timing and Sleep
The interplay between sleep, light exposure, and circadian rhythms is critical for health, yet it remains inadequately described in the everyday lives of parents with young infants.
Vaida Verhoef, Emma Visser, Karin Smolders, Niki Antypa, Yvonne de Kort   +4 more
doaj   +1 more source

Multimodal pragmatic assessment in healthy aging: The interplay with Executive Functioning, Theory of Mind and Cognitive Reserve

Acta Psychologica
Pragmatic competence is crucial for effective social interaction and well-being, and yet it tends to decline with age. While most research has focused on basic linguistic skills, the multimodal nature of communication and the cognitive processes that ...
A. Parola, I. Gabbatore, D. Hilviu, A. Marini, F.M. Bosco   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source