Results 51 to 60 of about 713,760 (296)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Teachers’ SEL Identity (SEL-ID): An Intersection Between Teacher Identity and Social and Emotional Learning (SEL)

open access: yesBehavioral Sciences
Although teacher identity and social–emotional learning (SEL) have been studied separately, little is known about how these constructs intersect in ways that explain why teachers’ social and emotional competence (SEC) does not always translate into ...
Zehra Kaplan, Mine Göl-Güven
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Empower instructors with actionable insights: Mine and visualize student written feedback for instructors’ reflection

open access: yesComputers and Education: Artificial Intelligence
Student feedback on teaching at the end of the semester is an important source of information for instructors to gain insights into the effectiveness of their teaching.
Feng Lin   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Agentes y moderadores en espacios verdes urbanos: una visión multiespecies

open access: yesRevista de Arquitectura (Bogotá)
En las últimas décadas, las soluciones basadas en la naturaleza (SbN) se han postulado como estrategias clave para enfrentar los desafíos ambientales producidos por el cambio climático.
Diana M Benjumea Mejía
doaj   +1 more source

Incorporating machine learning and social determinants of health indicators into prospective risk adjustment for health plan payments [PDF]

open access: gold, 2020
Jeremy Irvin   +9 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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