Results 61 to 70 of about 17,777,312 (301)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Higher Education: Increased and Equitable Access to Quality Learning Opportunities

, 2019
Given that many developing countries seek to increase participation in Higher Education (HE), COL will work with Ministries of Education and HE Institutions to support capacity building including the development and implementation of Open and Distance ...
Commonwealth of Learning
core   +1 more source

Identifying Professional Development in Teaching & Learning Needs in Higher Education: A Measure

Trends in Higher Education
The evolving landscape of higher education necessitates a re-evaluation of professional development (PD) frameworks to support instructors in enhancing their teaching practices.
Lyndon Lim, Che Yee Lye, Seo Hong Lim, Wei Ying Rebekah Lim, Cindy Neo, Pei Jun See   +5 more
doaj   +1 more source

Agency Leaders' Assessments of Feasibility and Desirability of Implementation of Evidence-Based Practices in Youth-Serving Organizations Using the Stages of Implementation Completion

Frontiers in Public Health, 2018
Background: This study examined influences on the decisions of administrators of youth-serving organizations to initiate and proceed with implementation of an evidence-based practice (EBP).Methods: Semi-structured interviews, developed using the Stages ...
Lawrence A. Palinkas, Mark Campbell, Lisa Saldana   +2 more
doaj   +1 more source

Mental health problems among young people in substance abuse treatment in Sweden

Substance Abuse Treatment, Prevention, and Policy, 2020
Background Young people with substance use problems face a high risk of co-occurring mental health problems, something that may involve a more difficult life situation, social problems as well as worse treatment outcomes.
Torkel Richert, Mats Anderberg, Mikael Dahlberg   +2 more
doaj   +1 more source

Psychometric properties of the Adolescent Resilience Questionnaire (ARQ) in a sample of Swedish adolescents

BMC Psychiatry, 2022
Background The importance of resilience, and interest in it, has increased markedly in recent years, based on the need to understand why some children and young people have a resilience to stress that others lack.
Doris Nilsson, Carl Göran Svedin, Frida Hall, Emelie Kazemi, Örjan Dahlström   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

SEL Is Adaptive: Exploring Implementation Integrity Through SEL Adaptations in OST Settings

Education Sciences
Although social emotional learning (SEL) is generally regarded as beneficial for children, there is an enduring tension between the need to observe fidelity to SEL programming (to reach desired outcomes) and the need to adapt SEL programming (to make ...
Natasha Raisch, Laura Stickle, Chelsea Rubin, Lillian Massaro, Cris Yanak-Cushman, Stephanie M. Jones, Rebecca Bailey   +6 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source