Results 101 to 110 of about 8,064,509 (338)
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Psychiatria i Psychologia Kliniczna, 2011 Introduction: The approach of alcohol-dependent people and medical personnel to alcohol-related problems may affect the efficacy of preventive and therapeutic measures aimed at alcohol-dependence treatment.
Piotr Ścisło +2 more
doaj
Humanitarian competencies of a doctor (cardiologist)
Российский кардиологический журнал, 2019 The article reveals the features of working with the patient as a social and psychological subject, who, in addition to somatic pathology, has an experience of the disease situation.
E. O. Taratukhin
doaj +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Long-term word frequency dynamics derived from Twitter are corrupted: A bespoke approach to detecting and removing pathologies in ensembles of time series [PDF]
arXiv, 2020 Maintaining the integrity of long-term data collection is an essential scientific practice. As a field evolves, so too will that field's measurement instruments and data storage systems, as they are invented, improved upon, and made obsolete. For data streams generated by opaque sociotechnical systems which may have episodic and unknown internal rule ...
arxiv
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source
New Microbes and New Infections, EarlyView., 2014 Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi +8 more
wiley +1 more source
Structured psychosocial stress and the US obesity epidemic [PDF]
arXiv, 2003 We examine the accelerating 'obesity epidemic' in the US from the perspective of generalized language-of-thought arguments relating a cognitive hypothalamic-pituitary-adrenal axis to an embedding context of structured psychosocial stress. From a Rate Distortion perspective, the obesity epidemic is an image of ratcheting social pathology -- indexed by ...
arxiv
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source