Results 101 to 110 of about 8,547,671 (360)

The impact of an emotionally expressive writing intervention on eating pathology in female students [PDF]

open access: yes, 2018
© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.Introduction: Previous research demonstrating emotional influences on eating and weight suggest that emotionally expressive writing may have a significant impact on ...
Cohen J.   +6 more
core   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

The city as one thing [PDF]

open access: yes, 2007
This paper summarises the latest theories in the field of space syntax. It opens with a discussion of the relationship between the form of urban grids and the process of how cities are formed by human activity; this is done by a comprehensive review of ...
Hillier, B, Vaughan, L
core  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Opinions ofpatients and medical personnel inoutpatient andinpatient health care, as related tothe causes andtreatment ofalcohol-dependence. Opinions ofpatients about alcoholism

open access: yesPsychiatria i Psychologia Kliniczna, 2011
Introduction: The approach of alcohol-dependent people and medical personnel to alcohol-related problems may affect the efficacy of preventive and therapeutic measures aimed at alcohol-dependence treatment.
Piotr Ścisło   +2 more
doaj  

Ethnolinguistic identity and social cognition: Language prejudice as hermeneutic pathology

open access: yesSign Systems Studies, 2007
Analysts studying the nexus between language and ethnic identity have characterized ethnolinguistic ideologies as the deep structure of overt language practices.
David Herman
doaj   +1 more source

A Review on the Applications of Crowdsourcing in Human Pathology

open access: yes, 2017
The advent of the digital pathology has introduced new avenues of diagnostic medicine. Among them, crowdsourcing has attracted researchers' attention in the recent years, allowing them to engage thousands of untrained individuals in research and ...
Alialy, Roshanak   +6 more
core   +2 more sources

Loss and psychosocial factors as determinants of quality of life in a cohort of earthquake survivors. [PDF]

open access: yes, 2015
BACKGROUND: Despite the existing evidence of a long lasting effect of disaster related experiences on physical and psychological health, few studies have evaluated long-term quality of life (QOL) outcomes of disaster survivors and the factors associated ...
Armenian, HK   +3 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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