Results 131 to 140 of about 3,513,455 (311)
Labour courts in Great Britain and Sweden: a self-service model v collective regulation [PDF]
, 2013 The institutions for adjudicating employment rights in Great Britain and Sweden are superficially similar – in both countries there are labour courts with lay judges and both countries are covered by European Union employment legislation.
Corby, Susan
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
EL SISTEMA EUROPEO DE DERECHOS FUNDAMENTALES TRAS LA ENTRADA EN VIGOR DEL TRATADO DE LISBOA
Lex Humana, 2011 Resumen: En 1947 se pusieron las bases de lo que llegaría a ser la Unión Europea, a modo de organización comercial para sectores concretos, complejo que iría creciendo, ampliándose los fines y la organización, a la par que se fraguaba un complejo ...
Lorenzo Martín-Retortillo Baquer
doaj
WHO OWNS NATURAL RESOURCES IN THE UNITED STATES AND CANADA? [PDF]
Property rights are social definitions; they exist as long as the society is willing to enforce them. If enforcement is missing, they cease to exist.
Marchak, M. Patricia
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
, 2023 The European Pillar of Social Rights (EPSR) sits at the fulcrum of EU social policy-making. As a formally non-binding interinstitutional proclamation composed of 20 social rights and principles, its (potential) effects are far from clear. Through a comprehensive empirical study, this thesis explores the effects of the EPSR on policy instruments ...
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Piero Calamandrei e la genesi dei diritti sociali [PDF]
Democrazia e Diritti SocialiThe paper analyses the genesis of social rights in the Italian legal system and examines the complex debate on the social question, which was animated by different awareness.
Giulio Donzelli
doaj
Cross-country analysis of correlation between protection of women's economic and social rights, health improvement and sustainabledevelopment. [PDF]
BMJ Open, 2019 Alaei K +6 more
europepmc +1 more source