Results 131 to 140 of about 3,546,996 (310)

Are there customary rights to plants?: an inquiry among the Baganda (Uganda), with special attention to gender [PDF]

open access: yes
"Debates around Common Property Resources and Intellectual Property Rights fail to consider traditional and indigenous rights regimes that regulate plant resource exploitation, establish bundles of powers and obligations for heterogeneous groups of users,
Howard, Patricia L., Nabanoga, Gorettie
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Increasing Copyright Protection for Social Media Users by Expanding Social Media Platforms\u27 Rights [PDF]

open access: yes, 2017
Social media platforms allow users to share their creative works with the world. Users take great advantage of this functionality, as Facebook, Instagram, Flickr, Snapchat, and WhatsApp users alone uploaded 1.8 billion photos per day in 2014.
Wichtowski, Ryan
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The effective assessment of clinical legal education [PDF]

open access: yes, 2003
In January 2003, a new unit was established under the auspices of the Human Rights and Social Justice Research Institute of London Metropolitan University to deal with human rights cases from Russia (see Leach, 2003).
Leach, Philip
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Migration Governance and Migration Rights in the Southern African Development Community (SADC): Attempts at Harmonization in a Disharmonious Region [PDF]

open access: yes, 2015
This paper examines prospects for enhanced regional migration governance and protection of migrants’ rights in the Southern African Development Community (SADC).
Crush, Jonathan, Dodson, Belinda
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Good Fences Make Good Neighbors: Endogenous Property Rights in a Game of Conflict [PDF]

open access: yes
This paper derives the conditions under which property rights can arise in an anarchy equilibrium. The creation of property rights requires that players devote part of their endowment to the public good of property rights protection.
David M. Bruner, John R. Boyce
core  

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