Results 111 to 120 of about 80,353 (310)

CRISPR/Cas9‐based white pupae mutant lines in Bactrocera spp. for sterile insect technique applications

Insect Science, EarlyView.
Bactrocera fruit flies are significant horticultural pests that cause major economic losses. A “neoclassical approach” incorporating genome editing via CRISPR/Cas9 to develop genetic sexing strains (GSS) could render the sterile insect technique (SIT) against these pests more efficient and cost‐effective.
Chrysanthi Ioannidou, Maria‐Eleni Gregoriou, Marc F. Schetelig, Elena Drosopoulou, Kostas D. Mathiopoulos, Kostas Bourtzis   +5 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

An evaluation of the effectiveness of a chemical additive based on sodium benzoate, potassium sorbate, and sodium nitrite on the fermentation and aerobic stability of corn silage [PDF]

, 2018
L. Kung, M. L. Smith, Erica Benjamim da Silva, Michelle Windle, Thiago Carvalho da Silva, S. A. Polukis   +5 more
openalex   +1 more source

Solid Shampoo Is Mostly Not Preserved, in Contrast to Liquid Shampoos Used in Hairdressing—A Market Survey in Four European Countries

Contact Dermatitis, EarlyView.
Most solid shampoos (68.6%) did not contain preservatives according to Annex V of the EU Cosmetics Regulation (EC 1223/2009), while all liquid shampoos did. The number of preservatives used was significantly greater in liquid shampoos. ABSTRACT Background Hairdressers are frequently exposed to shampoos, both from neat liquid products and dilutions ...
Wolfgang Uter, Anders B. Funch, Mikkel Bak Jensen, Christoffer Kursawe Larsen, Ying X. Teo, Jeanne D. Johansen, Carola Lidén, Ian R. White   +7 more
wiley   +1 more source

Contact Sensitization in Adults With Atopic Dermatitis: A 21‐Year Single‐Center Tertiary Experience

Contact Dermatitis, EarlyView.
A graphical abstract has been included as supplemental material. ABSTRACT Background Atopic dermatitis is a common chronic inflammatory skin condition. Data on contact sensitization in adults with atopic dermatitis remain limited. Objectives To investigate the prevalence of contact sensitization in adults with and without AD: Patients/Methods A ...
Francesca Caroppo, Anna Zambello, Giulia Biolo, Fortunato Cassalia, Laura Ventura, Anna Belloni Fortina   +5 more
wiley   +1 more source

Effect of Sodium Benzoate as an Add-on Therapy on the Clinical and Cognitive Symptoms of Schizophrenia: A Case Series [PDF]

Journal of Clinical and Diagnostic Research
Schizophrenia is understood as a construct of positive, negative, and cognitive symptoms. There has been considerable proof at a genetic, biochemical, and pharmacological level to support that N-methyl-D-aspartate Receptor (NMDAR) hypofunction is a key ...
Robin Victor, Priyaranjan Avinash, Rachit Singhania   +2 more
doaj   +1 more source

A comprehensive study on the production of potassium sorbate and sodium benzoate reference material in orange juice

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Controlling the content of preservatives in soft drinks is of paramount important for assessing their quality during production and consumption, as well as for ensuring consumer health. To effectively enhance laboratory capacity in preservatives analysis,
Le Manh Hung, Dang Huu Cuong, Nguyen Nhu Thuong, Dang Thi Oanh   +3 more
doaj   +1 more source

In vitro cytotoxicity of chemical preservatives on human fibroblast cells

Brazilian Journal of Pharmaceutical Sciences, 2018
Preservatives are widely used substances that are commonly added to various cosmetic and pharmaceutical products to prevent or inhibit microbial growth.
Daniel Gonsales Spindola, Andre Hinsberger, Valéria Maria de Souza Antunes, Luis Felipe Gomes Michelin, Claudia Bincoletto, Carlos Rocha Oliveira   +5 more
doaj   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source