Results 1 to 10 of about 9,216 (139)

Exogenous Melatonin Protects against Oxidative Damage to Membrane Lipids Caused by Some Sodium/Iodide Symporter Inhibitors in the Thyroid. [PDF]

Antioxidants (Basel), 2023
The thyroid gland is the primary site of sodium/iodide symporter (NIS), an intrinsic plasma membrane protein responsible for the active uptake of iodine, which is indispensable for thyroid hormone synthesis.
Gładysz AK, Stępniak J, Karbownik-Lewińska M.   +2 more
europepmc   +2 more sources

Co-Administration of Albumin and Furosemide in Acute Heart Failure with Diuretic Resistance

Acta Médica Portuguesa, 2023
Acute heart failure is a frequent cause of hospital admission in Portugal, and has an increasing tendency given the aging population. Although most admissions for acute heart failure are caused by congestive conditions, not all patients have a congestive
Jorge Fernandes, Rita Costa, Renato Guerreiro, Dulce Bonifácio, Ana Rodrigues, Célia Henriques, Patrícia Branco, Inês Araújo, Cândida Fonseca   +8 more
doaj   +1 more source

Critical Analysis of the Effects of SGLT2 Inhibitors on Renal Tubular Sodium, Water and Chloride Homeostasis and Their Role in Influencing Heart Failure Outcomes

Circulation, 2023
SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose and sodium in the early proximal renal tubule, but the magnitude and duration of any ensuing natriuretic or diuretic effect are the result of an interplay ...
M. Packer, C. Wilcox, J. Testani
semanticscholar   +1 more source

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.

PLoS Medicine, 2022
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk.
James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno   +25 more
doaj   +1 more source

Assessment of the hydroalcoholic extract and powder cocoa bean shell as corrosion inhibitors for carbon steel in sodium chloride solution

, 2021
Carbon steel is used in various applications because of its excellent weldability, good mechanical resistance and low cost. However, its application becomes restricted due to its low corrosion resistance in neutral and acidic media, and it is necessary ...
Mayara Cristina Fernandes de Carvalho, Iago Magella Fernandes Costa Rossi e Silva, Pâmara Larissa Alves Macedo, M. Tokumoto, R. S. D. Cruz, V. R. Capelossi   +5 more
semanticscholar   +1 more source

Chemical inhibitors as potential allied for CO2 replacement in gas hydrates reservoirs: sodium chloride case study

Proceedings of the 6th World Congress on Mechanical, Chemical, and Material Engineering, 2020
In previous experimental works we proved how the presence of sodium chloride may influence the replacement of methane contained into hydrate with carbon dioxide.
A. Gambelli, B. Castellani, M. Filipponi, A. Nicolini, F. Rossi   +4 more
semanticscholar   +1 more source

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux

Cellular Physiology and Biochemistry, 2014
Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco, Cristina Cosentino, Laura Sirna, Roberta Romano, Silvia Cursano, Alessandra Mongia, Giampaolo Pompeo, Julie di Bernardo, Claudio Ceccarelli, Giovanni Tallini, Kerry J. Rhoden   +10 more
doaj   +1 more source

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library.

Environmental Science and Technology, 2018
Thyroid uptake of iodide via the sodium-iodide symporter (NIS) is the first step in the biosynthesis of thyroid hormones that are critical for health and development in humans and wildlife.
Jun Wang, D. Hallinger, A. Murr, A. Buckalew, S. Simmons, S. Laws, T. Stoker   +6 more
semanticscholar   +1 more source

Sodium chloride inhibits effective bubbly drag reduction in turbulent bubbly Taylor–Couette flows [PDF]

Philosophical Transactions of the Royal Society A, 2022
Using the Taylor–Couette geometry we experimentally investigate the effect of salt on drag reduction caused by bubbles present in the flow. We combine torque measurements with optical high-speed imaging to relate the bubble size to the drag experienced ...
Luuk J. Blaauw, D. Lohse, S. Huisman
semanticscholar   +1 more source

Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) protects against focal cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation

Pharmaceutical Biology, 2022
Context Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) is a compound preparation commonly used for treating cerebral ischaemia/reperfusion injury in ischaemic stroke in China.
T. Zhu, Bin-Yu Fang, Xiang-bao Meng, Shu-xia Zhang, Hong Wang, Ge Gao, Fei Liu, Yu Wu, Jin Hu, Gui-Bo Sun, Xiao-Bo Sun   +10 more
semanticscholar   +1 more source