Results 1 to 10 of about 14,950 (202)

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Construction of a Fluorescence‐Based Logic Gate Seeing the Effect of Perchlorate Ions on Hemicyanine Dye–β‐Cyclodextrin Complexes to Certify Safe Drinking Water

ChemistryOpen, EarlyView.
A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M., Shalini Dyagala, Sairathna Choppella, Mahesh Kumar Ravva, Subit Kumar Saha   +4 more
wiley   +1 more source

Genomics‐assisted breeding for designing salinity‐smart future crops

Plant Biotechnology Journal, EarlyView.
This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza, Qamar U. Zaman, Sergey Shabala, Mark Tester, Rana Munns, Zhangli Hu, Rajeev K. Varshney   +6 more
wiley   +1 more source

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine‐Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms

Advanced Science, Volume 12, Issue 17, May 8, 2025.
This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li, Hongyuan Li, Hongshuang Wang, Xiaohui Wang   +3 more
wiley   +1 more source

Generation of Conformation‐Specific Monoclonal Antibodies for Integral Membrane Proteins

Current Protocols, Volume 5, Issue 5, May 2025.
Abstract Antibodies and their antigen‐binding fragments, including fragment antigen‐binding domains (Fabs) and single‐chain variable fragments (scFvs), are extraordinary tools in all fields of biology, particularly in neuroscience, where they have been utilized for imaging, detection, and quantification studies.
Natalie Sheldon, Gunasekaran Dhandapani, Junhoe Kim, Cathy J. Spangler, Chengli Fang, Jumi Park, Prashant Rao, Eric Gouaux   +7 more
wiley   +1 more source

Update of the Scientific Opinion on the risks for human health related to the presence of perchlorate in food

EFSA Journal, Volume 23, Issue 5, May 2025.
Abstract The European Commission asked EFSA to update its 2014 risk assessment on perchlorate in food. Perchlorate is a contaminant of both natural and anthropogenic sources present in food and drinking water. It is a substrate for the sodium iodide symporter (NIS) and competitively inhibits the uptake of iodide into the thyroid.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Aleksandra Buha Djordjevic, Thorhallur Halldorsson, Chantra Eskes, Olaf Mosbach‐Schulz, Francesca Riolo, Elena Rovesti, Efisio Solazzo, Alexios Zormpas, Tuuli Tauriainen, James Kevin Chipman   +27 more
wiley   +1 more source

Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair

Advanced Science, Volume 12, Issue 10, March 13, 2025.
This review offers a comprehensive overview of piezoelectric materials in antibacterial treatments, emphasizing the configuration of piezoelectric biomaterial, the mechanisms behind their antibacterial effects, and their current applications in tissue engineering.
Siyuan Shang, Fuyuan Zheng, Wen Tan, Zhengyi Xing, Siyu Chen, Fuli Peng, Xiang Lv, Duan Wang, Xiangdong Zhu, Jiagang Wu, Zongke Zhou, Xingdong Zhang, Xiao Yang   +12 more
wiley   +1 more source

Potential Health Impacts, Treatments, and Countermeasures of Martian Dust on Future Human Space Exploration

GeoHealth, Volume 9, Issue 2, February 2025.
Abstract The challenges of human space exploration produce some of humanity's greatest technological and scientific advances, not excluding innovations in medicine. The microgravity environment causes a host of physiological changes, and exposure to dust on the Moon caused considerable pulmonary distress to astronauts during the Apollo missions. As the
Justin L. Wang, Jeremy J. Rosenbaum, Ajay N. Prasad, Robert R. Raad, Esther J. Putman, Andrea D. Harrington, Haig Aintablian, Brian M. Hynek   +7 more
wiley   +1 more source

Genetic polymorphisms influencing antihypertensive drug responses

British Journal of Pharmacology, Volume 182, Issue 4, Page 929-950, February 2025.
Abstract Hypertension is a major contributor to cardiovascular disease and its associated morbidity and mortality. The low efficacy observed with some anti‐hypertensive therapies has been attributed partly to inter‐individual genetic variability. This paper reviews the major findings regarding these genetic variabilities that modulate responses to anti‐
Jana El Cheikh, Fouad Hamed, Hana Rifi, Ali H. Dakroub, Ali Hussein Eid   +4 more
wiley   +1 more source