Results 11 to 20 of about 14,950 (202)

Anoctamin 1 is Apically Expressed on Thyroid Follicular Cells and Contributes to ATP- and Calcium-Activated Iodide Efflux [PDF]

Cellular Physiology and Biochemistry, 2014
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Ceccarelli, Claudio, Cosentino, Cristina, Cursano, Silvia, di Bernardo, Julie, Iosco, Carmela, Mongia, Alessandra, Pompeo, Giampaolo, Rhoden, Kerry J., Romano, Roberta, Sirna, Laura, Tallini, Giovanni   +10 more
core   +4 more sources

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers:A mendelian randomization analysis [PDF]

PLoS Medicine, 2022
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk.
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core   +3 more sources

Exogenous Melatonin Protects against Oxidative Damage to Membrane Lipids Caused by Some Sodium/Iodide Symporter Inhibitors in the Thyroid. [PDF]

Antioxidants (Basel), 2023
The thyroid gland is the primary site of sodium/iodide symporter (NIS), an intrinsic plasma membrane protein responsible for the active uptake of iodine, which is indispensable for thyroid hormone synthesis.
Gładysz AK, Stępniak J, Karbownik-Lewińska M.   +2 more
europepmc   +2 more sources

High-Throughput Screening of ToxCast PFAS Chemical Library for Potential Inhibitors of the Human Sodium Iodide Symporter. [PDF]

Chem Res Toxicol, 2023
Over the past decade, there has been increased concern for environmental chemicals that can target various sites within the hypothalamic-pituitary-thyroid axis to potentially disrupt thyroid synthesis, transport, metabolism, and/or function.
Stoker TE, Wang J, Murr AS, Bailey JR, Buckalew AR.   +4 more
europepmc   +2 more sources

Co-Administration of Albumin and Furosemide in Acute Heart Failure with Diuretic Resistance

Acta Médica Portuguesa, 2023
Acute heart failure is a frequent cause of hospital admission in Portugal, and has an increasing tendency given the aging population. Although most admissions for acute heart failure are caused by congestive conditions, not all patients have a congestive
Jorge Fernandes, Rita Costa, Renato Guerreiro, Dulce Bonifácio, Ana Rodrigues, Célia Henriques, Patrícia Branco, Inês Araújo, Cândida Fonseca   +8 more
doaj   +1 more source

Critical Analysis of the Effects of SGLT2 Inhibitors on Renal Tubular Sodium, Water and Chloride Homeostasis and Their Role in Influencing Heart Failure Outcomes

Circulation, 2023
SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose and sodium in the early proximal renal tubule, but the magnitude and duration of any ensuing natriuretic or diuretic effect are the result of an interplay ...
M. Packer, C. Wilcox, J. Testani
semanticscholar   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22:Transporters [PDF]

, 2021
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective ...
Adam J Pawson, Alistair Mathie, Bruno Hagenbuch, Catriona M. H. Anderson, Christopher Southan, David T. Thwaites, Eamonn Kelly, Elena Faccenda, Emma L Veale, Gavin Stewart, James R. Hammond, Jamie A Davies, Jane F Armstrong, John A Peters, Jules C Hancox, Ken‐ichi Inui, Laura Amarosi, Paul A. Dawson, Philip Mark Beart, Simon D Harding, Stefan Broer, Stephan Kemp, Stephen P H Alexander, Tiziano Verri, Yoshikatsu Kanai   +24 more
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2023/24:Transporters [PDF]

, 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions ...
Alexander, Stephen P H, Amarosi, Laura, Anderson, Catriona M H, Armstrong, Jane F, Beart, Philip M, Broer, Stefan, Davies, Jamie A, Dawson, Paul A, Fabbro, Doriano, Faccenda, Elena, Gyimesi, Gergely, Hagenbuch, Bruno, Hammond, James R, Hancox, Jules C, Harding, Simon D, Hershfinkel, Michal, Inui, Ken-Ichi, Kanai, Yoshikatsu, Kelly, Eamonn, Kemp, Stephan, Kunji, Edmund R S, Mathie, Alistair A, Peters, John A, Stewart, Gavin, Tavoulari, Sotiria, Thwaites, David T, Veale, Emma L, Verri, Tiziano   +27 more
core   +3 more sources

Assessment of the hydroalcoholic extract and powder cocoa bean shell as corrosion inhibitors for carbon steel in sodium chloride solution

, 2021
Carbon steel is used in various applications because of its excellent weldability, good mechanical resistance and low cost. However, its application becomes restricted due to its low corrosion resistance in neutral and acidic media, and it is necessary ...
Mayara Cristina Fernandes de Carvalho, Iago Magella Fernandes Costa Rossi e Silva, Pâmara Larissa Alves Macedo, M. Tokumoto, R. S. D. Cruz, V. R. Capelossi   +5 more
semanticscholar   +1 more source

Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer [PDF]

, 2021
This article belongs to the Special Issue Role of Small GTPase Signaling in TumorigenesisThe functional expression of the sodium-iodide symporter (NIS) at the membrane of differentiated thyroid cancer (DTC) cells is the cornerstone for the use of ...
Bugalho, Maria João, Domingues, Rita, Faria, Márcia, Matos, Paulo, Silva, Ana Luísa   +4 more
core   +1 more source