Results 21 to 30 of about 4,509 (135)

Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions [PDF]

, 2015
Licensed by the Creative Commons Attribution ...
A Ene-Obong, A Lardner, AM Sidahmed, C Croia, C Gobelet, C Mauro, C Nathan, CH Chang, Claudio Mauro, Costantino Pitzalis, DK Finlay, DR Wahl, DW Jung, Elliot J. Bland, F Humby, F Vegran, Federica M. Marelli-Berg, Fulvio D’Acquisto, FW Fitch, G Yi, J Olloquequi, J Zhu, Joanne Smith, JR Doherty, K De Bock, K Fischer, KJ Livak, LZ Shi, M Buzzai, M Chabaud, M Kleinewietfeld, M Sukumar, Mauro Perretti, ME Morris, Michele Bombardieri, MJ Ovens, MM Delmastro-Greenwood, N Shyh-Chang, O Haworth, OR Colegio, Philippa Marrack, PP Hsu, R Haas, R Wang, RA Robergs, RD Michalek, Robert Haas, S Su, SJ Jarmin, SN Mueller, SP Young, SR Srinivas, SS Metkar, Suchita Nadkarni, T Hashimoto, T Hitosugi, T Montero-Melendez, T Soga, TC Leite, Trinidad Montero-Melendez, VA Gerriets, Vidalba Rocher-Ros, Y Cao   +62 more
core   +5 more sources

The Concise Guide to PHARMACOLOGY 2023/24:Transporters [PDF]

, 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions ...
Alexander, Stephen P H, Amarosi, Laura, Anderson, Catriona M H, Armstrong, Jane F, Beart, Philip M, Broer, Stefan, Davies, Jamie A, Dawson, Paul A, Fabbro, Doriano, Faccenda, Elena, Gyimesi, Gergely, Hagenbuch, Bruno, Hammond, James R, Hancox, Jules C, Harding, Simon D, Hershfinkel, Michal, Inui, Ken-Ichi, Kanai, Yoshikatsu, Kelly, Eamonn, Kemp, Stephan, Kunji, Edmund R S, Mathie, Alistair A, Peters, John A, Stewart, Gavin, Tavoulari, Sotiria, Thwaites, David T, Veale, Emma L, Verri, Tiziano   +27 more
core   +5 more sources

Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]

, 2016
Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P., Hofer, Anders, Pavlova, Anna, Ranjbarian, Farahnaz, Vodnala, Munender   +4 more
core   +1 more source

Chloride in Heart Failure:The Neglected Electrolyte [PDF]

, 2021
The increasing burden of heart failure (HF) and emerging knowledge regarding chloride as a prognostic marker in HF have increased the interest in the pathophysiology and interactions of chloride abnormalities with HF-related factors and treatments ...
Ezekowitz, Justin A., Julius, Florine E.C., McAlister, Finlay A., Pannu, Neesh, Sepehrvand, Nariman, van Norel, Margje R., Voors, Adriaan A., Zandijk, Arietje J.L.   +7 more
core   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models [PDF]

, 2014
Background: An in-depth understanding of the fundamental principles that regulate thyroid hormone homeostasis is critical for the development of new diagnostic and treatment ap-proaches for patients with thyroid disease.
Antonio C. Bianco, Apostolopoulos JJ, Balázs Gereben, Bernier-Valentin F, Bianco AC, Bianco AC, Bianco AC, Biddinger P, Brian W. Kim, Brooker G, Carey MF, Cawthorne C, David S. Sharlin, Delverdier M, Dolphin PJ, Dolphin PJ, Douglas Forrest, Escobar del Rey F, Everts ME, Forrest D, Freitas FRS, Frumess RD, Galbraith DW, Goodman MN, Graham R. Williams, Grant Anderson, Grewal A, Harper ME, Hilditch TE, Kaplan MM, Kasuga Y, Kirschbaum BJ, Kopp P, Larsen PR, Lazar MA, Leonard JL, Maria Jesus Obregon, Mebis L, Morreale de Escobar G, Morreale de Escobar G, Muller A, Nilsson M, Nilsson M, Nunes MT, Pantos C, Pappas M, Pazos-Moura CC, Pennock GD, Peter A. Kopp, Refetoff S, Ring GC, Robin P. Peeters, Roy E. Weiss, Samuel Refetoff, Sap J, Sato M, Sellers EA, Sharifi J, Silva JE, Silva JE, Simonides WS, Sjöberg M, Smith QR, Taylor CR, Valerie Anne Galton, Visser TJ, Wagschal A, Warner S. Simonides, Wu SY, Xiao Hui Liao, Yen PM, Young JB, Zuckier LS   +72 more
core   +5 more sources

The Use of LeuT as a Receptor Model for Antidepressant Development [PDF]

, 2010
Selective serotonin re-uptake inhibitors (SSRIs) have been considered to be promising drugs in psychiatric practice because of their selectivity to serotonin re-uptake transporter (SERT).
Rustanti, L. (Lina)
core  

The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH [PDF]

, 2015
Although the anti-cancer properties of 3BP have been described previously, its selectivity for cancer cells still needs to be explained. In the work reported here we characterized the kinetic parameters of radiolabelled [14C]-3BP uptake in three breast ...
Ana Preto, Ana Ribeiro, Becker, Birsoy, de Oliveira, Donohoe, Fung, Fátima Baltazar, Gallagher, Guo, Halestrap, Hanahan, João Azevedo-Silva, Kirk, Klier, Ko, Ko, Ko, Ko H. Young, Kobayashi, Le Floch, Li, Majkowska-Skrobek, Margarida Casal, Mathupala, Mathupala, Matsumoto, Miranda-Goncalves, Odília Queirós, Ovens, Parks, Pastorino, Pereira da Silva, Pertega-Gomes, Peter L. Pedersen, Philp, Pinheiro, Pinheiro, Pinheiro, Pinheiro, Queiros, Schaefer, Sonveaux, Szablewski, Tang, Thangaraju, Tsai, Vander Heiden, Vossen, Warburg, Zhao   +50 more
core   +1 more source

Functional interplay between CFTR and pendrin: physiological and pathophysiological relevance [PDF]

, 2022
: The transport of chloride and bicarbonate across epithelia controls the pH and volume of the intracellular and luminal fluids, as well as the systemic pH and vascular volume.
Dossena, Silvia, Tamma, Grazia
core   +2 more sources

Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack

New Phytologist, Volume 249, Issue 3, Page 1124-1144, February 2026.
Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos, The Dan Pham, Thibaut Perez, Myriam Ben Amar, Claire Corratgé‐Faillie, François Barbier, Benoit Lacombe   +6 more
wiley   +1 more source