Results 41 to 50 of about 433,143 (306)

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]

, 1984
A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings, David W. Bilheimer, Goldstein, Joseph L. Goldstein, Michael S. Brown, Pittman, Schneider, Schneider, Scott M. Grundy, Thomas E. Starzl   +9 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The role of contact angle in the thermal conductivity of microencapsulated phase change material suspensions

Advances in Mechanical Engineering, 2017
The purpose of this article is to investigate the effect of the wettability on the thermal conductivity of microencapsulated phase change material suspensions.
Zhongzhu Qiu, Ping Le, Peng Li, Chengfang Qin, Weiting Jiang, Puyan Zheng, Tao Zhang, Chunying Li   +7 more
doaj   +1 more source

Inactivation of Prions by Acidic Sodium Dodecyl Sulfate [PDF]

Journal of Virology, 2006
ABSTRACTPrompted by the discovery that prions become protease-sensitive after exposure to branched polyamine dendrimers in acetic acid (AcOH) (S. Supattapone, H. Wille, L. Uyechi, J. Safar, P. Tremblay, F. C. Szoka, F. E. Cohen, S. B. Prusiner, and M. R. Scott, J.
David, Peretz, Surachai, Supattapone, Kurt, Giles, Julie, Vergara, Yevgeniy, Freyman, Pierre, Lessard, Jiri G, Safar, David V, Glidden, Charles, McCulloch, Hoang-Oanh B, Nguyen, Michael, Scott, Stephen J, Dearmond, Stanley B, Prusiner   +12 more
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Allergic Potency of Japanese Cedar Pollen Cry j 1 Is Reduced by a Low Concentration of Hypochlorous Acid Generated by Electolysis

Allergology International, 2009
Background: Although Japanese cedar (Cryptomeria japonica) pollinosis has developed into a health problem, few methods eradicate indoor allergens completely.
Tetsuya Terada, Yoko Akimoto, Sawako Hyo, Daisuke Suzuki, Kazuhiko Tanaka, Hiroshi Takenaka   +5 more
doaj   +1 more source

The binding of dyestuffs by proteins [PDF]

, 1950
Thesis (M.A.)--Boston ...
Scully, Margaret A
core   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Examination of mixed sodium dodecyl sulfate – 1-butanol micelles with molecular dynamics

Вісник Харківського національного університету: Серія xімія, 2022
Properties of mixed micelles composed of sodium n-dodecyl sulfate surfactant and 1-butanol co‑surfactant were examined using molecular dynamics simulation for three experimentally observed compositions. The aggregation number varied in the range of 30 to
Illia Kononenko, Vladimir Farafonov
doaj   +1 more source