Results 91 to 100 of about 626 (142)

Preferences for Attributes of Sodium Oxybate Treatment: A Discrete Choice Experiment in Patients with Narcolepsy

Patient Preference and Adherence, 2022
Jordan Dubow,1 Alon Y Avidan,2 Bruce Corser,3 Amod Athavale,4 David Seiden,1 Clete Kushida5 1Avadel Pharmaceuticals, Chesterfield, MO, USA; 2Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 3Sleep Management ...
Dubow J, Avidan AY, Corser B, Athavale A, Seiden D, Kushida C   +5 more
doaj  

Comparative efficacy of new wake-promoting agents for narcolepsy-a network meta-analysis

BMC Neurology
Background As a rare sleep disorder, narcolepsy is treated with various therapeutic options. This article systematically analyzes the efficacy and safety of novel approved wake-promoting drugs.
Zian Yan, Jiwei Li, Yixin Yu, Shenghan Qiu, Bing Wang, Jiyou Tang   +5 more
doaj   +1 more source

Sodium oxybate for idiopathic REM sleep behavior disorder: a report on two patients

, 2017
Background REM-sleep behavior disorder (RBD) therapy is based on small to medium-sized case series, as no large controlled clinical trials have been performed.
Moghadam, Keivan Kaveh, PLAZZI, GIUSEPPE, Moghadam Keivan Kaveh, Pizza Fabio, Primavera, Alberto, Plazzi Giuseppe, Ferri, Raffaele, Primavera Alberto, PIZZA, FABIO, Ferri Raffaele   +9 more
core   +1 more source

How once-nightly sodium oxybate is processed in the body in healthy volunteers: a plain language summary

Journal of Comparative Effectiveness Research
What is this summary about? This is a plain language summary of an article originally published in the journal Sleep Medicine. Narcolepsy is a sleep condition in which people have periods of extreme sleepiness during the day.
Richard Bogan, Michael J Thorpy, Sarah Berkowitz, Jennifer Gudeman   +3 more
doaj   +1 more source

Sodium oxybate – new views on an old candidate This presentation will outline the outcome of a clinical development program, including a Phase 3 study, on sodium oxybate in the treatment of alcohol dependence

European Psychiatry
Sodium oxybate (SMO) has shown efficacy in the treatment of alcohol withdrawal syndrome (AWS) and in the maintenance of abstinence in alcohol dependent (AD) patients in a series of pilot randomized controlled trials.
J. Guiraud
doaj   +1 more source

Acamprosate in the treatment of alcoholism: a budget impact analysis for the National Health Service in Italy

Substance Abuse and Rehabilitation, 2012
Giorgio L Colombo,1,2 Sergio Di Matteo,2 Giacomo Bruno21Department of Drug Sciences, School of Pharmacy, University of Pavia, Pavia, Italy; 2S.A.V.E. – Studi Analisi Valutazioni Economiche, Milan, ItalyObjective: Alcohol dependence is a common ...
Colombo GL, Di Matteo S, Bruno G
doaj  

Living with Narcolepsy: Current Management Strategies, Future Prospects, and Overlooked Real-Life Concerns

Nature and Science of Sleep, 2020
Emily C Barker,1 Julie Flygare,2 Shalini Paruthi,3,4 Katherine M Sharkey5– 7 1Case Western Reserve University School of Medicine, Department of Pediatrics, Cleveland, OH, USA; 2Project Sleep, Los Angeles, CA, USA; 3Sleep Medicine and Research ...
Barker EC, Flygare J, Paruthi S, Sharkey KM   +3 more
doaj  

A Patient-centric Clinical Trial Design to Comprehensively Evaluate Low-Sodium Oxybate in People with Idiopathic Hypersomnia or Narcolepsy

Neurology and Therapy
Introduction Low-sodium oxybate (LXB; Xywav®) is approved to treat idiopathic hypersomnia in adults and excessive daytime sleepiness or cataplexy in individuals aged ≥ 7 years with narcolepsy.
Deborah A. Nichols, Teresa L. Steininger, Douglas S. Fuller, M. Todd Kirby, Emily C. Barker, Marisa Whalen, Jessica K. Alexander, Sarah Akerman, David T. Plante   +8 more
doaj   +1 more source

Treatment with Sodium Oxybate in Children and Young Adults – a Register Study in Halland and Västra Götaland

, 2016
Background: Narcolepsy is a chronical neurological disease with a prevalence of 0,02-0,05 % in the western world. A massive increase in incidence occurred after the vaccination with Pandemrix against the H1N1-influenza.
Björck, Per
core  

Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study

, 2014
INTRODUCTION: Narcolepsy is associated with obesity though it is uncertain whether this is caused by changes in glucose and fat metabolism. Therefore, we performed a detailed analysis of systemic energy homeostasis in narcolepsy patients, and ...
Kalsbeek, A., Donjacour, CEHM Claire, Pijl, H., Donjacour, Claire E H M, Donjacour, C.E., Aziz, N. Ahmad, Overeem, S Sebastiaan, Lammers, Gert Jan Gert, Aziz, N Ahmad, Donjacour, Claire E. H. M., Overeem, Sebastiaan, Kalsbeek, Andries, Lammers, Gert Jan, Lammers, G.J., Aziz, A., Aziz, N.A., Pijl, Hanno, Donjacour, C.E.H.M., Overeem, S.   +18 more
core   +1 more source