Results 81 to 90 of about 626 (142)

Narcolepsy: current treatment options and future approaches

Neuropsychiatric Disease and Treatment, 2008
Michel BilliardDepartment of Neurology, Gui de Chauliac Hospital, Montpellier, FranceAbstract: The management of narcolepsy is presently at a turning point. Three main avenues are considered in this review: 1) Two tendencies characterize the conventional
Michel Billiard
doaj  

Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory

, 2012
Sodium oxybate (SO) is a GABAβ agonist used to treat the sleep disorder narcolepsy. SO was shown to increase slow wave sleep (SWS) and EEG delta power (0.75-4.5 Hz), both indexes of NREM sleep (NREMS) intensity and depth, suggesting that SO enhances ...
Schwartz, S., Lecciso, G., Constantinescu, Irina Oana, Vienne, Julie, Franken, P., Constantinescu, I., Vienne, J., Tafti, M., Heinzer, Raphael, Franken, Paul, Schwartz, Sophie, Heinzer, R., Lecciso, Gianpaolo, Tafti, Mehdi   +13 more
core   +1 more source

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

JMIR Research Protocols
BackgroundCatatonia is a severe psychomotor syndrome predominantly associated with depressive, bipolar, and psychotic disorders.
Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel   +18 more
doaj   +1 more source

Criteria for Gauging Response to Sodium Oxybate for Narcolepsy

, 2018
Our objective was to define responder criteria using an anchor-based approach for frequency of cataplexy attacks and excessive daytime sleepiness in narcolepsy patients undergoing sodium oxybate treatment. We used pooled data from two randomized, placebo-
Terri E. Weaver (7931498), Alana D. Steffen (7931495), Chinglin Lai (5169872)   +2 more
core  

Improved vigilance after sodium oxybate treatment in narcolepsy: a comparison between in-field and in-laboratory measurements

, 2016
This two-centre observational study of vigilance measurements assessed the feasibility of vigilance measurements on multiple days using the Sustained Attention to Response Task and the Psychomotor Vigilance Test with portable task equipment, and ...
van Schie, M.K.M., Fronczek, R Rolf, Overeem, S Sebastiaan, Lammers, Gert Jan Gert, Baumann, CR, Werth, E., Overeem, S, Schie, M.K.M. van, Lammers, G J, Baumann, C R, Werth, E, Fronczek, R., Schie, MKM van, Baumann, C.R., van Schie, M K M, Fronczek, R, Lammers, G.J., Overeem, S.; id_orcid, Schie, M.K. van, Werth, E; https://orcid.org/, Overeem, S.   +20 more
core   +1 more source

Practical Guidance for Initiation and Management of Patients on Once-Nightly Sodium Oxybate for Narcolepsy Treatment: Modified Delphi Panel Consensus Recommendations

Neurology and Therapy
Introduction Despite its strong recommendation for treatment of excessive daytime sleepiness (EDS), cataplexy, and disease severity associated with narcolepsy by the American Academy of Sleep Medicine, sodium oxybate (SXB) remains underutilized.
Monique Mulvany, Ellen Wermter, Maggie Lavender, Heidy Merius, Cecile Martin, Amber Burns, Jamie Simmons   +6 more
doaj   +1 more source

Symptom Severity and Treatment Satisfaction in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE)

Nature and Science of Sleep, 2023
Logan Douglas Schneider,1 Joanne Stevens,2 Aatif M Husain,3 Diane Ito,4 Douglas S Fuller,5 Phyllis C Zee,6 Wayne Macfadden2 1Stanford University Sleep Medicine Center, Stanford University School of Medicine, Stanford, CA, USA; 2Global Medical Affairs ...
Schneider LD, Stevens J, Husain AM, Ito D, Fuller DS, Zee PC, Macfadden W   +6 more
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Trends in Prescription of Stimulants and Narcoleptic Drugs in Switzerland: Longitudinal Health Insurance Claims Analysis for the Years 2014-2021

JMIR Public Health and Surveillance
BackgroundStimulants are potent treatments for central hypersomnolence disorders or attention-deficit/hyperactivity disorders/attention deficit disorders but concerns have been raised about their potential negative consequences and their increasing ...
Tamara Scharf, Carola A Huber, Markus Näpflin, Zhongxing Zhang, Ramin Khatami   +4 more
doaj   +1 more source

Is Sodium Oxybate a Safe and Effective Treatment for Patients with Fibromyalgia

, 2012
Objective: The objective of this systematic review is to determine whether or not Sodium Oxybate is a safe and effective treatment of pain and sleep-related symptoms of fibromyalgia.
Grandinette, Britanie A
core  

Treatment paradigms for cataplexy in narcolepsy: past, present, and future

Nature and Science of Sleep, 2015
Todd J Swick1–4 1Department of Neurology, University of Texas School of Medicine-Houston, Houston; 2The Sleep Center at North Cypress Medical Center, Cypress; 3Apnix Sleep Diagnostics, Houston; 4Neurology and Sleep Medicine Consultants, Houston, TX,
Swick TJ
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