Results 121 to 130 of about 562,472 (163)

Efficacy of Once-Nightly Sodium Oxybate in Patients with Narcolepsy: Post Hoc Analyses of Sensitivity, Effect Size, and Numbers Needed to Treat from the Phase 3 REST-ON Trial. [PDF]

CNS Drugs
Roth T, Thorpy MJ, Kushida CA, Gudeman J.   +3 more
europepmc   +1 more source

Efficacy and Safety of Sodium Oxybate in Isolated Focal Laryngeal Dystonia: A Phase IIb Double-Blind Placebo-Controlled Cross-Over Randomized Clinical Trial. [PDF]

Ann Neurol
Simonyan K, O'Flynn LC, Hamzehei Sichani A, Frucht SJ, Rumbach AF, Sharma N, Song PC, Worthley A.   +7 more
europepmc   +1 more source

Letter to the Editor regarding: “Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary” by R. Rosenberg et al

Neurology and Therapy
Thomas Roth
doaj   +1 more source

Assessing Early Efficacy After Initiation of Once-Nightly Sodium Oxybate (ON-SXB; FT218) in Participants with Narcolepsy Type 1 or 2: A Post Hoc Analysis from the Phase 3 REST-ON Trial. [PDF]

CNS Drugs
Krahn L, Roy A, Winkelman JW, Morse AM, Gudeman J.   +4 more
europepmc   +1 more source

Use of sodium oxybate for the treatment of alcohol withdrawal syndrome in patients with acute alcohol-associated hepatitis: A 4-patient case report. [PDF]

Medicine (Baltimore)
Caputo F, Casabianca A, Brazzale C, Lungaro L, Costanzini A, Caio G, De Giorgio R, Testino G, Piscaglia F, Caraceni P.   +9 more
europepmc   +1 more source

Improvement in sleep latency with extended-release once-nightly sodium oxybate for the treatment of adults with narcolepsy: Analysis from the phase 3 REST-ON clinical trial. [PDF]

Sleep Med X
Thorpy MJ, Kushida CA, Bogan R, Winkelman J, Ohayon MM, Shapiro CM, Gudeman J.   +6 more
europepmc   +1 more source

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Sodium oxybate for narcolepsy

Expert Review of Neurotherapeutics, 2006
Sodium oxybate (Xyrem), also known as gamma-hydroxybutyric acid, is the only therapeutic specifically approved in the USA for the treatment of cataplexy in narcolepsy. The US FDA has recently expanded its indication to include excessive daytime sleepiness associated with narcolepsy.
exaly   +3 more sources

Safety and efficacy of long-term use of sodium oxybate for narcolepsy with cataplexy in routine clinical practice [PDF]

Sleep Medicine, 2017
Background Sodium oxybate is licensed in Europe for the treatment of narcolepsy with cataplexy in adults. The aim of this study was to assess the efficacy and safety of sodium oxybate in clinical practice in patients with narcolepsy and cataplexy ...
Brian Kent, Guy Leschziner, Joerg Sebastian Steier   +2 more
exaly   +2 more sources

Sodium-oxybate

Reactions Weekly, 2019
  +7 more sources