Results 91 to 100 of about 2,895,022 (317)
Object-Oriented Simulation Model Generation in an Automated Control Software Development Framework [PDF]
Organised by: Cranfield UniversityThe automated development of control software for mechatronic systems requires the integration of control models for design and verification purposes.
van Tooren, M. J. L., Foeken, M. J.
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Understanding and Supporting Software Design in Model-Based Software Engineering [PDF]
Model-Based Software Engineering (MBSE) is a software development approach in which models can serve a multitude of purposes. On the one hand, models can be used for ideation, to stimulate creative thinking, and facilitate communication.
Jolak, Rodi
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Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Concurrent design of embedded control software [PDF]
Embedded software design for mechatronic systems is becoming an increasingly time-consuming and error-prone task. In order to cope with the heterogeneity and complexity, a systematic model-driven design approach is needed, where several parts of the ...
Voeten, J.P.M. +7 more
core +2 more sources
This paper presents a geometry-driven framework for temporally stable 2D isoline reconstruction from particle-based simulation data. Unlike conventional Marching Squares methods, which assume grid-aligned scalar fields and often suffer from boundary ...
Yu-Bin Kwon, Jong-Hyun Kim
doaj +1 more source
The design of software interfaces in Spec [PDF]
Spec, a language for giving black-box specifications in the early stages of software design is presented. The underlying computational model combines message passing with temporal events in a precisely defined way. The features of the language, especially those important for large-scale design, are presented by example. >
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Contribuições do design na produção de software educacional [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de ProduçãoO presente trabalho apresenta as contribuições que o design pode oferecer ao desenvolvimento de softwares educacionais.
Fenner, Rita de Cássia
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sustainability Design and Software: The Karlskrona Manifesto [PDF]
Sustainability has emerged as a broad concern for society. Many engineering disciplines have been grappling with challenges in how we sustain technical, social and ecological systems.
Penzenstadler, Birgit +6 more
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