Results 81 to 90 of about 2,532,329 (269)

A Survey on Autism Care, Diagnosis, and Intervention Based on Mobile Apps Focusing on Usability and Software Design. [PDF]

Sensors (Basel), 2023
Liu X, Zhao W, Qi Q, Luo X.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Design and Implementation of a Musical System for the Development of Creative Activities Through Electroacoustics in Educational Contexts

Signals
In the field of music education, the incorporation of technology originally designed for professionals presents both significant opportunities and challenges.
Esteban Peris, Adolf Murillo, Jesús Tejada   +2 more
doaj   +1 more source

Updating Model of Software Component Trustworthiness Based on Users Feedback

IEEE Access, 2019
The software trustworthiness measurement is one of the hot topics. Software component technology is the mainstream technology of software development.
Baohua Wang, Yixiang Chen, Shun Zhang, Hengyang Wu   +3 more
doaj   +1 more source

A Data Transformation Methodology to Create Findable, Accessible, Interoperable, and Reusable Health Data: Software Design, Development, and Evaluation Study. [PDF]

J Med Internet Res, 2023
Sinaci AA, Gencturk M, Teoman HA, Laleci Erturkmen GB, Alvarez-Romero C, Martinez-Garcia A, Poblador-Plou B, Carmona-Pírez J, Löbe M, Parra-Calderon CL.   +9 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Variability-Aware Machine Learning Model Selection: Feature Modeling, Instantiation, and Experimental Case Study

IEEE Access
The emergence of machine learning (ML) has led to a transformative shift in software techniques and guidelines for building software applications that support data analysis process activities such as data ingestion, modeling, and deployment. Specifically,
Cristina Tavares, Nathalia Nascimento, Paulo Alencar, Donald Cowan   +3 more
doaj   +1 more source

A user task design notation for improved software design. [PDF]

PeerJ Comput Sci, 2021
Ozcan E, Topalli D, Tokdemir G, Cagiltay NE.   +3 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

[Model construction and software design of computed tomography radiation system based on visualization]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023
Liu Y, Meng T, Zhang H, Lu H.
europepmc   +1 more source