Results 71 to 80 of about 6,316,092 (301)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Looking back or looking forward in corpus linguistics: What can the last 20 years suggest about the next? [PDF]
Ibérica, 2012 Starting with a description of the software and hardware used for corpus linguistics in the late 1980s to early 1990s, this contribution discusses difficulties faced by the software designer when attempting to allow users to study text.
Mike Scott
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Redundancy in the Software Design Process is Essential for Designing Correct Software.
ERCIM News, 2014 Researchers at Eindhoven University of Technology in the Netherlands plead the case for more redundancy in software development as a way of improving the quality of outcomes and reducing overall costs.
Brand, van den, M.G.J., Groote, J.F.
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Active interaction strategy generation for human-robot collaboration based on trust
Visual Computing for Industry, Biomedicine, and ArtIn human-robot collaborative tasks, human trust in robots can reduce resistance to them, thereby increasing the success rate of task execution. However, most existing studies have focused on improving the success rate of human-robot collaboration (HRC ...
Yujie Guo +3 more
doaj +1 more source
Graphical ModelsWe present an efficient message aggregation algorithm FastClothGNN for Graph Neural Networks (GNNs) specifically designed for real-time cloth simulation in virtual try-on systems.
Yang Zhang, Kailuo Yu, Xinyu Zhang
doaj +1 more source
Communications software performance prediction [PDF]
, 1997 Software development can be costly and it is important that confidence in a software system be established as early as possible in the design process.
Akehurst, David H. +3 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Knowledge modeling for software design [PDF]
This paper develops a modeling framework for systems engineering that encompasses systems modeling, task modeling, and knowledge modeling, and allows knowledge engineering and software engineering to be seen as part of a unified developmental process ...
Gaines, Brian R., Shaw, Mildred L. G.
core +1 more source