Results 61 to 70 of about 14,237,440 (297)

Needs’ elaboration between users, designers and project leaders: Analysis of a design process of a virtual reality-based software [PDF]

, 2014
Context: The participation of users in the design process is recognized as a positive and a necessary element as artifacts suit their needs. Two complementary approaches of users’ involvement co-exist: the user-centered design and the participatory ...
LOUP-ESCANDE, Emilie, RICHIR, Simon, CHRISTMANN, Olivier, BURKHARDT, Jean-Marie   +3 more
core   +1 more source

Aligned and realistic latent diffusion for text-to-motion generation

Visual Computing for Industry, Biomedicine, and Art
Text-to-motion generation aims to synthesize semantically consistent and naturally coherent motion sequences from natural language descriptions. Given the continuous nature of human motion, diffusion models operating in a continuous latent space offer ...
Zhaowu Li, Rui Liu, Deheng Zhu, Dongsheng Zhou, Xiaopeng Wei   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi, Virpi Roto, Markus Joutsela, Joutsela, Markus   +3 more
core   +1 more source

Towards Building a Uniform Cloud Database Representation for Data Interchange

Annals of the West University of Timisoara: Mathematics and Computer Science, 2016
The paper proposes design principles for data representation and simplification in order to design cloud services for data exchange between various information systems. We use equivalence algorithms and canonical representation in the cloud database. The
Andreica Alina
doaj   +1 more source

Bellini’s Correspondence: a Digital Scholarly Edition for a Multimedia Museum

Umanistica Digitale, 2019
Within the “Museo Virtuale della Musica BellinInRete” project, a corpus of letters, written by the renowned composer Vincenzo Bellini (1801 - 1835) from Catania, will be encoded and made publicly available. This contribution aims at illustrating the part
Angelo Mario Del Grosso, Erica Capizzi, Salvatore Cristofaro, Maria Rosa De Luca, Emiliano Giovannetti, Simone Marchi, Graziella Seminara, Daria Spampinato   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A robust watermarking algorithm against JPEG compression based on multiscale autoencoder

IET Image Processing
The network structure of digital watermarking algorithm based on deep learning is usually encoder‐noise layer‐decoder. Most of the existing encoders suffer from the problem of insufficient feature extraction, and the introduction of simulated ...
Wei Zhang, Rongrong Chen, Bin Wang
doaj   +1 more source