Results 61 to 70 of about 21,707,590 (377)
Tinker 8: Software Tools for Molecular Design.
Journal of Chemical Theory and Computation, 2018 The Tinker software, currently released as version 8, is a modular molecular mechanics and dynamics package written primarily in a standard, easily portable dialect of Fortran 95 with OpenMP extensions.
Joshua A. Rackers +8 more
semanticscholar +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Hip joint contact forces and muscle contributions between bounce and standard squats
BMC Sports Science, Medicine and RehabilitationBackground Bounce squats, involving a rapid eccentric-concentric transition, are used in strength training to enhance force production via the stretch-shortening cycle.
Taewoong Kong +4 more
doaj +1 more source
Design and Development of Software Tools for Bio-PEPA [PDF]
, 2009 This paper surveys the design of software tools for the Bio-PEPA process algebra. Bio-PEPA is a high-level language for modelling biological systems such as metabolic pathways and other biochemical reaction networks.
Duguid, Adam +4 more
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
IEEE Access, 2023 Disturbances are widespread in biochemical systems. Nowadays, prevalent single-loop control strategies only take external disturbances into account. However, internal perturbations that threaten the stability of biochemical systems are invariably ignored.
Huihui Xue +3 more
doaj +1 more source
Concurrent Design of Embedded Control Software [PDF]
, 2009 Embedded software design for mechatronic systems is becoming an increasingly time-consuming and error-prone task. In order to cope with the heterogeneity and complexity, a systematic model-driven design approach is needed, where several parts of the ...
Broenink, Jan +3 more
core +4 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A robust watermarking algorithm against JPEG compression based on multiscale autoencoder
IET Image ProcessingThe network structure of digital watermarking algorithm based on deep learning is usually encoder‐noise layer‐decoder. Most of the existing encoders suffer from the problem of insufficient feature extraction, and the introduction of simulated ...
Wei Zhang, Rongrong Chen, Bin Wang
doaj +1 more source