Results 71 to 80 of about 21,707,590 (377)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 1980 © 1980 California Institute of Technology. I wish to thank Dr. Frederick B. Thompson for his patient guidance and help during my graduate studies at Caltech.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
TechnologiesEffective communication is crucial in daily life, and for people with hearing disabilities, sign language is no exception, serving as their primary means of interaction. Various technologies, such as cochlear implants and mobile sign language translation
Gerardo García-Gil +4 more
doaj +1 more source
Towards Building a Uniform Cloud Database Representation for Data Interchange
Annals of the West University of Timisoara: Mathematics and Computer Science, 2016 The paper proposes design principles for data representation and simplification in order to design cloud services for data exchange between various information systems. We use equivalence algorithms and canonical representation in the cloud database. The
Andreica Alina
doaj +1 more source
Bellini’s Correspondence: a Digital Scholarly Edition for a Multimedia Museum
Umanistica Digitale, 2019 Within the “Museo Virtuale della Musica BellinInRete” project, a corpus of letters, written by the renowned composer Vincenzo Bellini (1801 - 1835) from Catania, will be encoded and made publicly available. This contribution aims at illustrating the part
Angelo Mario Del Grosso +7 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A Model for Quality Optimization in Software Design Processes [PDF]
, 2005 The main objective of software engineers is to design and implement systems that implement all functional and non-functional requirements. Unfortunately, it is very difficult or even generally impossible to deliver a software system that satisfies all ...
Aksit, Mehmet +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
How to design gamification? A method for engineering gamified software
Information and Software Technology, 2017 Context Since its inception around 2010, gamification has become one of the top technology and software trends. However, gamification has also been regarded as one of the most challenging areas of software engineering.
Benedikt Morschheuser +3 more
semanticscholar +1 more source