Results 81 to 90 of about 21,707,590 (377)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Evidence-based Tool for Triggering School Closures during Influenza Outbreaks, Japan

open access: yesEmerging Infectious Diseases, 2009
Guidelines available to school administrators to support school closure decisions during influenza outbreaks are usually not evidence-based. Using empirical data on absentee rates of elementary school students in Japan, we developed a simple and ...
Asami Sasaki   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Active interaction strategy generation for human-robot collaboration based on trust

open access: yesVisual Computing for Industry, Biomedicine, and Art
In human-robot collaborative tasks, human trust in robots can reduce resistance to them, thereby increasing the success rate of task execution. However, most existing studies have focused on improving the success rate of human-robot collaboration (HRC ...
Yujie Guo   +3 more
doaj   +1 more source

FastClothGNN: Optimizing message passing in Graph Neural Networks for accelerating real-time cloth simulation

open access: yesGraphical Models
We present an efficient message aggregation algorithm FastClothGNN for Graph Neural Networks (GNNs) specifically designed for real-time cloth simulation in virtual try-on systems.
Yang Zhang, Kailuo Yu, Xinyu Zhang
doaj   +1 more source

Looking back or looking forward in corpus linguistics: What can the last 20 years suggest about the next? [PDF]

open access: yesIbérica, 2012
Starting with a description of the software and hardware used for corpus linguistics in the late 1980s to early 1990s, this contribution discusses difficulties faced by the software designer when attempting to allow users to study text.
Mike Scott
doaj  

Altimeter waveform software design [PDF]

open access: yes
Techniques are described for preprocessing raw return waveform data from the GEOS-3 radar altimeter. Topics discussed include: (1) general altimeter data preprocessing to be done at the GEOS-3 Data Processing Center to correct altimeter waveform data for
Brown, G. S.   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Survey on Software-Defined Wireless Sensor Networks: Challenges and Design Requirements

open access: yesIEEE Access, 2017
Software defined networking (SDN) brings about innovation, simplicity in network management, and configuration in network computing. Traditional networks often lack the flexibility to bring into effect instant changes because of the rigidity of the ...
H. Kobo, A. Abu-Mahfouz, G. Hancke
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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