Results 81 to 90 of about 6,225,690 (315)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Variability-Aware Machine Learning Model Selection: Feature Modeling, Instantiation, and Experimental Case Study

open access: yesIEEE Access
The emergence of machine learning (ML) has led to a transformative shift in software techniques and guidelines for building software applications that support data analysis process activities such as data ingestion, modeling, and deployment. Specifically,
Cristina Tavares   +3 more
doaj   +1 more source

Ageing as a software design flaw. [PDF]

open access: yesGenome Biol, 2023
de Magalhães JP.
europepmc   +1 more source

Utilizing FM software in collaborative design-learning

open access: yes, 2008
In this paper, we describe a case study of computer-supported collaborative learning in design using OpenLearn FlashMeeting software, a video conferencing tool.
Ferreira, Giselle   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Updating Model of Software Component Trustworthiness Based on Users Feedback

open access: yesIEEE Access, 2019
The software trustworthiness measurement is one of the hot topics. Software component technology is the mainstream technology of software development.
Baohua Wang   +3 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Hardware/Software Co-design for Particle Swarm Optimization Algorithm [PDF]

open access: yes
[[abstract]]This paper presents a hardware/software (HW/SW) co-design approach using SOPC technique and pipeline design method to improve the performance of particle swarm optimization (PSO) for embedded applications. Based on modular design architecture,
Li, Shih-an
core   +1 more source

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