Results 41 to 50 of about 15,432,329 (305)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
CLEI Electronic JournalEducation in Software Engineering traditionally focuses on techniques used in the classroom that generate stress and disinterest in the topics taught; therefore, a significant challenge to the use of more effective and motivating teaching methods to ...
Sergio Galvan-Cruz +4 more
doaj +1 more source
Web Engineering as a Specialization of Software Engineering: Differences in Project Management Education [PDF]
Journal of Systemics, Cybernetics and Informatics, 2005 We present the motivation and our concept of introducing "Web Engineering" as a specialization of our "Software Engineering" curriculum. Our main focus lies on the differences in project management education for both areas as well as the necessary ...
Herwig Mayr
doaj
Generic Skills in Software Engineering Master Thesis Projects : Towards Rubric-Based Evaluation
, 2009 There has been much recent interest in how to help students in higher education develop their generic skills, especially since this is a focus of the Bologna process that aims to standardize European higher education.
Feldt, Robert, +9 more
core +1 more source
, 2022 Erden, Zuhal/0000-0002-4860-4271; TURHAN, Cihan/0000-0002-4248-431X; Say, Bilge/0000-0001-9276-729XBased on the multidisciplinary needs of today's complex and innovative technology, accreditation bodies of engineering demand proof of multidisciplinary ...
Say, Bilge, Erden, Zühal, Turhan, Cihan
core +1 more source
Team Composition in Software Engineering Education [PDF]
, 2023 One of the objectives of software engineering education is to make students to learn essential teamwork skills. This is done by having the students work in groups for course assignments.
Hashmi, Sajid Ibrahim, Markkula, Jouni
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Освітній вимір, 2023 Objective: This study aims to develop a comprehensive methodology for integrating cloud-based learning tools into software engineering education for students in higher education institutions (HEIs). Research tasks: The research encompasses exploring the
Andrii M. Striuk
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source