Results 41 to 50 of about 150,847,779 (255)

Soft Finger Modelling and Co-Simulation Control towards Assistive Exoskeleton Hand Glove

Micromachines, 2021
The soft pneumatic actuators of an assistive exoskeleton hand glove are here designed. The design of the actuators focuses on allowing the actuator to perform the required bending and to restrict elongation or twisting of the actuator.
Mohammed N. El-Agroudy, Mohammed I. Awad, Shady A. Maged   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Embedded System Simulation Using Renode

Engineering Proceedings
In the automotive industry, the reduction of development costs is of key importance. The development of electrical hardware is an expensive, time-consuming process with a lot of development stages (e.g., prototyping, electrical testing, mechanical ...
Ferenc Speiser, István Szalay, Dénes Fodor   +2 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Loop B is a major structural component of the 5-HT3 receptor [PDF]

, 2008
The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J., Thompson, A.J., M. Lochner, Lummis, S. C. R., Lummis, S.C.R., S. C. R. Lummis, Lochner, M., A. J. Thompson, Lochner, Martin, Thompson, Andrew James   +9 more
core   +2 more sources

Real time implementation for robust adaptive sliding mode predictive control of PMSM

Unconventional Resources
Model Predictive Control is recognized as a promising approach for electric drives, with particular interest in the development of robust and high-performance predictive models.
Rachid Ibrahimi, Mohamed said Adouairi, Abdennabi Morchid, Badre Bossoufi, Paweł Skruch, Saleh Mobayen   +5 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A survey of software development practices in the New Zealand software industry [PDF]

, 2000
We report on the software development techniques used in the New Zealand software industry, paying particular attention to requirements gathering. We surveyed a selection of software companies with a general questionnaire and then conducted in-depth ...
Greg Reeve, Groves, Lindsay, Mark Utting, Reeves, Steve, Ray Nickson, Reeve, Greg, Steve Reeves, Utting, Mark, Lindsay Groves, Nickson, Ray   +9 more
core   +1 more source

Collision Avoidance Mechanism for Swarms of Drones

Sensors
This article presents a new approach to collision avoidance in drone swarms, designed for operations in large drone swarms and dynamic environments. The mechanism uses distributed communication, where drones share information about their positions and ...
Dariusz Marek, Piotr Biernacki, Jakub Szyguła, Adam Domański, Marcin Paszkuta, Marta Szczygieł, Marcel Król, Konrad Wojciechowski   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source