Results 61 to 70 of about 1,870,230 (325)

BOA: Framework for Automated Builds [PDF]

open access: yes, 2003
Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple ...
Ratnikova, N.
core   +1 more source

A software architecture for autonomous maintenance scheduling: Scenarios for UK and European Rail [PDF]

open access: yes, 2016
A new era of automation in rail has begun offering developments in the operation and maintenance of industry standard systems. This article documents the development of an architecture and range of scenarios for an autonomous system for rail maintenance ...
Blacktop, K.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effort-Aware Fault-Proneness Prediction Using Non-API-Based Package-Modularization Metrics

open access: yesMathematics
Source code complexity of legacy object-oriented (OO) software has a trickle-down effect over the key activities of software development and maintenance. Package-based OO design is widely believed to be an effective modularization. Recently, theories and
Mohsin Shaikh   +3 more
doaj   +1 more source

Empirical Study on the Evolution of Developer Social Networks

open access: yesIEEE Access, 2018
Software development is incredibly complex. Specifically, open-source software (OSS) development requires developers to collaborate with each other to conduct their work.
Mohamed Abdelrahman Aljemabi   +1 more
doaj   +1 more source

Software Architecture of Code Analysis Frameworks Matters: The Frama-C Example

open access: yes, 2015
Implementing large software, as software analyzers which aim to be used in industrial settings, requires a well-engineered software architecture in order to ease its daily development and its maintenance process during its lifecycle.
Signoles, Julien
core   +4 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Software maintenance: an approach towards control

open access: yesProceedings IEEE International Conference on Software Maintenance. ICSM 2001, 2002
In this paper the software maintenance process will be looked at in more detail from a control point of view. From this it can be seen that in most situations no proper control mechanisms exist and that even the basic requirements for control are not fulfilled. The remainder of the paper will be devoted towards describing a basic approach that provides
Kusters, R.J., Heemstra, F.J.
openaire   +5 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Maintenance of Automated Test Suites in Industry: An Empirical study on Visual GUI Testing

open access: yes, 2016
Context: Verification and validation (V&V) activities make up 20 to 50 percent of the total development costs of a software system in practice. Test automation is proposed to lower these V&V costs but available research only provides limited empirical ...
Alégroth, Emil   +2 more
core   +1 more source

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