Results 61 to 70 of about 1,789,157 (322)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Design and Implementation of JPEG 2000 Image Compression using FPGA
Journal of Engineering and Sustainable Development, 2006 This paper investigates the use of a Field Programmable Gate Array (FPGA Xilinx Virtex-II) to perform hardware implementation for low speed part of JPEG2000 to achieve a real time JPEG2000 system.
Munther N. B. Al-Tikriti +2 more
doaj
Novel method to forecast software aging problems
The Journal of Engineering, 2019 As software system becomes complex and large, some phenomena, performance degradation, error service, and even the abrupt system outage, have been found in the operating system, web server, and even in the security system.
Yongquan Yan
doaj +1 more source
BOA: Framework for Automated Builds [PDF]
, 2003 Managing large-scale software products is a complex software engineering task. The automation of the software development, release and distribution process is most beneficial in the large collaborations, where the big number of developers, multiple ...
Ratnikova, N.
core +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
A multiprocess quality model: identification of of key processes in the integration approach [PDF]
, 2012 In this paper we investigate the use of multiprocess quality model in the adoption of process improvement frameworks. We analyze an improvement effort based on multiple process quality models adoption.
Abd. Rahman, Aedah +2 more
core
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Clone Detection and Elimination for Haskell [PDF]
, 2010 Duplicated code is a well known problem in software maintenance and refactoring. Code clones tend to increase program size and several studies have shown that duplicated code makes maintenance and code understanding more complex and time consuming.
Brown, Christopher, Thompson, Simon
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Applied Computer Systems, 2021 Energy efficiency in mobile computing is really an important issue these days. Owing to the popularity and prevalence of Android operating system among the people, a great number of Android smartphone applications have been developed and proliferated by ...
Qasim Awais +3 more
doaj +1 more source