Results 51 to 60 of about 7,115,919 (304)

Modeling and Security in Cloud Ecosystems

open access: yesFuture Internet, 2016
Clouds do not work in isolation but interact with other clouds and with a variety of systems either developed by the same provider or by external entities with the purpose to interact with them; forming then an ecosystem.
Eduardo B. Fernandez   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Applying Scrum and Organizational Patterns to Multi-site Software Development

open access: yes, 2007
This paper describes a pattern language for managing multi-site software projects which aims at minimizing the main problems present on the multi-site software development context. The practices and patterns of the proposed language were first identified
Cordeiro, Lucas   +2 more
core   +1 more source

Degrees of tenant isolation for cloud-hosted software services: a cross-case analysis

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2018
A challenge, when implementing multi-tenancy in a cloud-hosted software service, is how to ensure that the performance and resource consumption of one tenant does not adversely affect other tenants.
Laud Charles Ochei   +2 more
doaj   +1 more source

Patterns in Teaching Software Development [PDF]

open access: yes, 2004
This paper summarizes the results of Workshop #14 held at ECOOP 2003. The goal of this one-day workshop was to discuss ideas on what and how to teach Software Development. The workshop focused on using patterns and concrete examples. Participants were encouraged to submit a small but concrete project (documentation and the running application).
Erzsébet Angster   +2 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

7 Dimensions of software change patterns

open access: yesScientific Reports
Evolving software is a highly complex and creative problem in which a number of different strategies are used to solve the tasks at hand. These strategies and reoccurring coding patterns can offer insights into the process.
Mario Janke, Patrick Mäder
doaj   +1 more source

Architectural Patterns for Blockchain Systems and Application Design

open access: yesApplied Sciences, 2023
Blockchain technology has gained popularity in various applications, including finance transactions and beyond. However, developing blockchain application systems is challenging due to stringent quality requirements, such as performance, scalability, and
Fouzia Alzhrani   +2 more
doaj   +1 more source

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