Results 71 to 80 of about 7,115,919 (304)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Framework for Patterns in Gaia: A case-study with Organisations
, 2004 The agent-oriented approach has been successfully applied to the solution of complex problems in dynamic open environments. However, to extend its use to mainstream computing and industrial environments, appropriate software tools are needed.
Luck, Michael +4 more
core +2 more sources
RipleyGUI: software for analyzing spatial patterns in 3D cell distributions
Frontiers in Neuroinformatics, 2013 The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationship in great detail.
Kristin eHansson +3 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
API Misuse Detection Tool for Secure Software Development
, 2023 Application Programming Interfaces (APIs) in cryptography typically impose concealed usage constraints. The violations of these usage constraints can lead to software crashes or security vulnerabilities.
Myoungkyu Song (14179850)
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Software patterns to improve knowledge transfer: an experiment. [PDF]
Patterns for software development have been a hot topic for some time within the object-oriented community. Patterns are part of a software engineering problem-solving discipline. It all started with Design Patterns [11], but gradually patterns were used
De Rore, Lotte +3 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Software Design Guidelines for Usability [PDF]
, 2011 For years, the Human Computer Interaction (HCI) community has crafted usability guidelines that clearly define what characteristics a software system should have in order to be easy to use.
Carvajal García, Laura Elena +1 more
core