Results 81 to 90 of about 7,115,919 (304)
Integration Patterns Development for Enterprise Software Systems
Безопасность информационных технологий, 2010 The work concerns the pattern building for heterogeneous enterprise information systems (IS). Quite a heavy data burden has been accumulated by the enterprises, and it tends to increase further.
S. V. Zykov
doaj
Identifying change patterns in software history
CoRR, 2013 Traditional algorithms for detecting differences in source code focus on differences between lines. As such, little can be learned about abstract changes that occur over time within a project. Structural differencing on the program's abstract syntax tree reveals changes at the syntactic level within code, which allows us to further process the ...
Jason Dagit, Matthew J. Sottile
openaire +4 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Defect patterns and structural properties in a mature well-specified software system [PDF]
, 2008 Software engineering is not an empirically based discipline. As a result, many of its practices are based on little more than a generally agreed feeling that something may be true.
Hopkins, Tim, Hatton, Leslie
core
Software Defect Prediction Using Heterogeneous Ensemble Classification Based on Segmented Patterns
Applied Sciences, 2020 Software defect prediction is a promising approach aiming to improve software quality and testing efficiency by providing timely identification of defect-prone software modules before the actual testing process begins.
Hamad Alsawalqah +6 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A methodology to assess the impact of design patterns on software quality
, 2012 Context Software quality is considered to be one of the most important concerns of software production teams. Additionally, design patterns are documented solutions to common design problems that are expected to enhance software quality.
Apostolos Ampatzoglou +5 more
core +1 more source
PatEvol – A pattern language for evolution in component-based software architectures [PDF]
, 2013 Modern software systems are prone to a continuous evolution under frequently varying requirements. Architecture-centric software evolution (ACSE) enables change in system structure and behavior while maintaining a global view of software to address ...
Fawad Khaliq (12621274) +8 more
core +2 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source