Results 91 to 100 of about 7,115,919 (304)
Checklist for a Software Management Plan
, 2016 It is easy to concentrate on short-term issues when developing research software. Getting publications, collaboration with others and the demands of a daily research routine can all conspire to prevent proper planning for the development of research ...
The Software Sustainability Institute
core +1 more source
Software energy profiling: comparing releases of a software product [PDF]
, 2016 In the quest for energy efficiency of Information and Communication Technology, so far research has mostly focused on the role of hardware. However, as hardware technology becomes more sophisticated, the role of software becomes crucial.
Lago, Patricia +21 more
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Package Patterns for Visual Architecture Recovery [PDF]
, 2006 Recovering the architecture is the first step towards reengineering a software system. Many reverse engineering tools use top-down exploration as a way of providing a visual and interactive process for architecture recovery.
M. Lanza +5 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
An Evaluation of ADLs on Modeling Patterns for Software Architecture [PDF]
, 2007 Architecture patterns provide solutions to recurring design problems at the architecture level. In order to model patterns during software architecture design, one may use a number of existing Architecture Description Languages (ADLs), including the UML,
Avgeriou, Paris; id_orcid +4 more
core +1 more source
Patterns for cleaning up bug data
, 2022 S.26-28Bug reports provide insight about the quality of an evolving software and about its development process. Such data, however, is often incomplete and inaccurate, and thus should be cleaned before analysis.
Chavez, C., Souza, R., Bittencourt, R.
core +1 more source