Results 91 to 100 of about 1,924,275 (351)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

A QUESTIONNAIRE BASED METHOD FOR CMMI LEVEL 2 MATURITY ASSESSMENT

Havacılık ve Uzay Teknolojileri Dergisi, 2009
CMMI has gained widespread acceptance as a viable software process assessment model. In this study, we take up CMMI, and consider the first maturity level or level 2 of the model for companies new to CMMI or just beginning to adopt CMMI in their ...
Fatih Yolcular, Şenol Zafer Erdoğan
doaj  

On the Role of Software Quality Management in Software Process Improvement [PDF]

, 2016
Software Process Improvement (SPI) programs have been implemented, inter alia, to improve quality and speed of software development. SPI addresses many aspects ranging from individual developer skills to entire organizations. It comprises, for instance, the optimization of specific activities in the software lifecycle as well as the creation of ...
Wiedemann Jacobsen, Jan, Kuhrmann, Marco, Münch, Jürgen, Diebold, Philipp, Felderer, Michael   +4 more
openaire   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Persuading developers to buy into software process improvement: a local opinion and empirical evidence [PDF]

, 2003
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Baddoo, N., Hall, T., Rainer, A.
core  

Speech Recognition Software—An Improvement to the Transcription Process?

Forum: Qualitative Social Research, 2008
The study outlined in this paper addresses the question: Does the use of speech recognition software allow a faster transcription of interview and audio recordings than traditional modes of transcription?
Thorsten Dresing, Thorsten Pehl, Claudia Lombardo   +2 more
doaj  

Process Correlation Analysis Model for Process Improvement Identification

The Scientific World Journal, 2014
Software process improvement aims at improving the development process of software systems. It is initiated by process assessment identifying strengths and weaknesses and based on the findings, improvement plans are developed.
Su-jin Choi, Dae-Kyoo Kim, Sooyong Park
doaj   +1 more source

Improvement of the Dynamic Software Birthmark Process by Reducing the Time of the Extraction

International Journal of Networked and Distributed Computing (IJNDC), 2018
It is a quite tough task to detect the stolen programs since there is a quite huge number of programs in the world. The dynamic software birthmarks were proposed to detect the suspects of plagiarisms based on the runtime behavior of the programs.
Takanori Yokoi, Haruaki Tamada
doaj   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Combining Capability Assessment and Value Engineering: a New Two-dimensional Method for Software Process Improvement [PDF]

Journal of Systemics, Cybernetics and Informatics, 2008
During the last decades software process improvement (SPI) has been recognized as a usable possibility to increase the quality of software development. Implemented SPI investments have often indicated increased process capabilities as well. Recently more
Pasi Ojala
doaj