Results 101 to 110 of about 1,924,275 (351)

A method to define process capability profiles from the characteristics of very small software enterprises

open access: yesCLEI Electronic Journal, 2010
This work presents a method for the definition of process capability profiles lined up with the specific business model of small software companies. The developed method is made up of a process, artifacts and guides that assist to obtain process profiles,
Cristiano Schwening, Marcello Thiry
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

A cloud software life cycle process (CSLCP) model

open access: yesAin Shams Engineering Journal, 2021
Small to medium-sized enterprises take advantage of the strengths and opportunities of cloud computing. These enterprises require a well-defined software process model to produce reliable and quality cloud software, given their limited resources ...
Amira A. Alshazly   +3 more
doaj  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Improvement of software process estimation. Applied case of software area in Barranquilla [PDF]

open access: yes, 2015
Summary-The present paper is the result of the following investigation: “Design of a model to improve the cost estimation processes for software developing companies”. It is presented a revision of the literature at an international level for identifying
Mercado Caruso, Nohora Nubia   +4 more
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

A Process Asset Library to support Software Process Improvement in Small Settings [PDF]

open access: yes, 2008
A main factor to the success of any organization process improvement effort is the Process Asset Library implementation that provides a central database accessible by anyone at the organization.
Calvo-Manzano Villalón, José Antonio   +3 more
core   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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