Results 81 to 90 of about 260,965 (273)
Electron energy relaxation by phonons in the Kondo condensate
, 2006 We have used normal metal-insulator-superconductor tunnel junctions as thermometers at sub-Kelvin temperatures to study the electron-phonon (e-p) interaction in thin Aluminum films doped with Manganese, as a function of Manganese concentration.
Enss C. +5 more
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Quantum metrology of solid-state single-photon sources using photon-number-resolving detectors
New Journal of Physics, 2019 Quantum-light sources based on semiconductor quantum dots (QDs) are promising candidates for many applications in quantum photonics and quantum communication. Important emission characteristics of such emitters, namely the single-photon purity and photon
Martin von Helversen +9 more
doaj +1 more source
Radon exhalation rate for phosphate rocks samples using alpha track detectors
Journal of Radiation Research and Applied Sciences, 2016 Solid state nuclear track detectors are used in very broad fields of technical applications and successfully applied in different areas of environmental physics and geophysics. Radon concentration and surface exhalation rate for phosphate samples from El-
Hesham A. Yousef +3 more
doaj +1 more source
Iron charge states observed in the solar wind [PDF]
, 1983 Solar wind measurements from the ULECA sensor of the Max-Planck-Institut/University of Maryland experiment on ISEE-3 are reported. The low energy section of approx the ULECA sensor selects particles by their energy per charge (over the range 3.6 keV/Q to
Galvin, A. B. +5 more
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Advanced technical developments in support of scientific experiments in space [PDF]
A technique was developed for preparing solid state, lithium-drifted silicon detectors. Hollow cylindrical detectors were built and tested for possible use as anticoincidence shields to replace conventional plastic scintillators and photomultipliers.
Lamport, J. E.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source