Results 1 to 10 of about 7,329 (254)
Nanoscale Research Letters, 2018 Solid-state nanopore has captured the attention of many researchers due to its characteristic of nanoscale. Now, different fabrication methods have been reported, which can be summarized into two broad categories: “top-down” etching technology and ...
Zhishan Yuan +5 more
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Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor [PDF]
Sensors, 2023 Protein aggregation is linked to many chronic and devastating neurodegenerative human diseases and is strongly associated with aging. This work demonstrates that protein aggregation and oligomerization can be evaluated by a solid-state nanopore method at
Mitu C. Acharjee +7 more
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Microfluidic Systems Applied in Solid-State Nanopore Sensors [PDF]
Micromachines, 2020 Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study.
Jiye Fu +4 more
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Controllable Shrinking Fabrication of Solid-State Nanopores
Micromachines, 2022 Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy.
Xin Lei +4 more
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Controlling DNA Translocation Through Solid-state Nanopores [PDF]
Nanoscale Research Letters, 2020 Compared with the status of bio-nanopores, there are still several challenges that need to be overcome before solid-state nanopores can be applied in commercial DNA sequencing. Low spatial and low temporal resolution are the two major challenges.
Zhishan Yuan +4 more
doaj +3 more sources
Ribosome Fingerprinting with a Solid-State Nanopore. [PDF]
ACS Sens, 2020 AbstractNanopores hold great potential for the analysis of complex biological molecules at the single entity level. One particularly interesting macromolecular machine is the ribosome, responsible for translating mRNA into proteins. In this study, we use a solid-state nanopore to fingerprint 80S ribosomes and polysomes from a human neuronal cell line ...
Raveendran M +4 more
europepmc +4 more sources
Solid-State Nanopore Single-Molecule Analysis of SARS-CoV-2 N Protein: From Interaction Exploration to Small-Molecule Antagonism [PDF]
SensorsThe COVID-19 pandemic caused by the SARS-CoV-2 virus has exposed the urgency of research on rapid and efficient virus detection and strategies to inhibit its replication. Previous studies have mostly focused on traditional immunoassay or optical methods,
Xiaoqing Zeng +15 more
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Solid-state nanopore hydrodynamics and transport. [PDF]
Biomicrofluidics, 2019 The resistive pulse method based on measuring the ion current trace as a biomolecule passing through a nanopore has become an important tool in biotechnology for characterizing molecules. A detailed physical understanding of the translocation process is essential if one is to extract the relevant molecular properties from the current signal.
Ghosal S, Sherwood JD, Chang HC.
europepmc +4 more sources
Thermostable virus portal proteins as reprogrammable adapters for solid-state nanopore sensors [PDF]
Nature Communications, 2018 Solid state nanopores are robust but the sizing can be variable, whereas protein nanopores are precisely sized but lack robustness. Here the authors cork a solid state nanopore with the DNA-translocating portal protein from the virus G20c to obtain a ...
Benjamin Cressiot +4 more
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Wafer-scale fabrication of solid-state nanopore array with a novel SpacerX process [PDF]
Microsystems & NanoengineeringSolid-state nanopores (SSNPs) have emerged as a transformative platform in nanotechnology and biotechnology, yet their application is limited by the lack of cost-effective, reproducible fabrication technology.
Lihuan Zhao +3 more
doaj +2 more sources