Results 231 to 240 of about 20,246 (268)

Periodontitis in Patients With Severe Obesity: From the Oral and Gut Microbiota Dysregulation to the Visceral Adipose Tissue Inflammatory and Metabolic Disorders

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
In patients with severe obesity, periodontitis is associated with oral microbiota dysbiosis which influences gut microbiota composition by increasing Proteobacteria proportion. These alterations are linked to systemic immune and metabolic changes, including higher circulating levels of anti‐Porphyromonas gingivalis lgG and deregulated lipid profile ...
Katy Thouvenot, Flavie Serrat, Victorine Lenclume, Eric Doussiet, Eugeni Belda, Janice Taïlé, Rohia Alili, Philippe Rondeau, Karine Clément, Olivier Meilhac, Nathalie Le Moullec, Marie‐Paule Gonthier   +11 more
wiley   +1 more source

Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites

Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer, Jan Mathis Hornbostel, Richard Prediger, Sebastian Kluck, Michael Daub, Cornelia Lee‐Thedieck, Frederik Kotz‐Helmer   +6 more
wiley   +1 more source

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Recent Progress in Solid‐State Nanopores

Advanced Materials, 2018
AbstractThe solid‐state nanopore has attracted much attention as a next‐generation DNA sequencing tool or a single‐molecule biosensor platform with its high sensitivity of biomolecule detection. The platform has advantages of processability, robustness of the device, and flexibility in the nanopore dimensions as compared with the protein nanopore, but ...
Kidan Lee, Kyeong‐Beom Park, Hyung‐Jun Kim, Jae‐Seok Yu, Hongsik Chae, Hyun‐Mi Kim, Ki‐Bum Kim   +6 more
openaire   +4 more sources

Solid-state nanopores

Nature Nanotechnology, 2007
The passage of individual molecules through nanosized pores in membranes is central to many processes in biology. Previously, experiments have been restricted to naturally occurring nanopores, but advances in technology now allow artificial solid-state nanopores to be fabricated in insulating membranes.
Cees Dekker
openaire   +4 more sources

Fabrication of solid-state nanopores

Nanotechnology, 2022
Abstract Nanopores are valuable single-molecule sensing tools that have been widely applied to the detection of DNA, RNA, proteins, viruses, glycans, etc. The prominent sensing platform is helping to improve our health-related quality of life and accelerate the rapid realization of precision medicine.
Kabin Lin, Chen Chen, Congsi Wang, Peiyuan Lian, Yan Wang, Song Xue, Jingjie Sha, Yunfei Chen   +7 more
openaire   +2 more sources

Chemically Modified Solid-State Nanopores

Nano Letters, 2007
Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used to fabricate synthetic nanopores in thin solid-state membranes with subnanometer resolution. Here we report a new class of chemically modified nanopore sensors. We describe two approaches for monolayer coating of nanopores: (1) self-assembly from solution,
Meni, Wanunu, Amit, Meller
openaire   +2 more sources

Rescalable solid-state nanopores

AIP Conference Proceedings, 2017
Nanopores in 10–30 nm thickness Si4N3 membranes were milled using Ga+ ions. Dose dependence of the hole diameter and shape was established and explained as resulting from the intensity distribution of the focused ion beam. The initial diameter of the milled pore is dependent on the full-width half-maximum of the axial portion of the beam, whereas shape
Armandas Balčytis, Cleménce Briosne-Fréjaville, Adrien Mau, Xijun Li, Saulius Juodkazis   +4 more
openaire   +1 more source

Microfluidic multiplexing of solid-state nanopores

Journal of Physics: Condensed Matter, 2017
Although solid-state nanopores enable electronic analysis of many clinically and biologically relevant molecular structures, there are few existing device architectures that enable high-throughput measurement of solid-state nanopores. Herein, we report a method for microfluidic integration of multiple solid-state nanopores at a high density of one ...
Tarun Jain, Benjamin C Rasera, Ricardo Jose S Guerrero, Jong-Min Lim, Rohit Karnik   +4 more
openaire   +2 more sources

Solid-State Nanopore Technologies for Nanopore-Based DNA Analysis

Nanomedicine, 2007
Nanopore-based DNA analysis is a new single-molecule technique that involves monitoring the flow of ions through a narrow pore, and detecting changes in this flow as DNA molecules also pass through the pore. It has the potential to carry out a range of laboratory and medical DNA analyses, orders of magnitude faster than current methods.
Ken, Healy, Birgitta, Schiedt, Alan P, Morrison   +2 more
openaire   +2 more sources

DNA Origami Gatekeepers for Solid‐State Nanopores

Angewandte Chemie, 2012
DNA has it covered: DNA origami gatekeeper nanoplates convert nanopores in solid-state membranes into versatile devices for label-free macromolecular sensing applications. The custom apertures in the nanoplates can be chemically addressed for sequence-specific detection of DNA.
Ruoshan Wei, Thomas G. Martin, Ulrich Rant, Hendrik Dietz   +3 more
openaire   +2 more sources