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DNA Origami Gatekeepers for Solid‐State Nanopores
Angewandte Chemie, 2012DNA has it covered: DNA origami gatekeeper nanoplates convert nanopores in solid-state membranes into versatile devices for label-free macromolecular sensing applications. The custom apertures in the nanoplates can be chemically addressed for sequence-specific detection of DNA.
Ruoshan Wei +3 more
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Rescalable solid-state nanopores
AIP Conference Proceedings, 2017Nanopores in 10–30 nm thickness Si4N3 membranes were milled using Ga+ ions. Dose dependence of the hole diameter and shape was established and explained as resulting from the intensity distribution of the focused ion beam. The initial diameter of the milled pore is dependent on the full-width half-maximum of the axial portion of the beam, whereas shape
Armandas Balčytis +4 more
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Solid-State Nanopore Technologies for Nanopore-Based DNA Analysis
Nanomedicine, 2007Nanopore-based DNA analysis is a new single-molecule technique that involves monitoring the flow of ions through a narrow pore, and detecting changes in this flow as DNA molecules also pass through the pore. It has the potential to carry out a range of laboratory and medical DNA analyses, orders of magnitude faster than current methods.
Ken, Healy +2 more
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Solid-state nanopores and nanopore arrays optimized for optical detection
Nanoscale, 2014Controllable reduction of the local fluorescence around solid-state nanopores and nanopore arrays enables optical recognition of molecular translocations and a route towards massively-parallel detection.
Furat, Sawafta +4 more
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Fabrication of solid‐state nanopores and its perspectives
ELECTROPHORESIS, 2015Nanofluidics is becoming an extensively developing technique in the field of bioanalytical chemistry. Nanoscale hole embed in an insulating membrane is employed in a vast variety of sensing platforms and applications. Although, biological nanopores have several attractive characteristics, in this paper, we focused on the solid‐state nanopores due to ...
Jiri, Kudr +6 more
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On Induced Surface Charge in Solid-State Nanopores
Langmuir, 2020Solid-state nanopores constitute a versatile platform for study of ion transport in nanoconfinement. The electrical double layer (EDL) plays a vital role in such nanoconfinements, but effects of induced surface charge on the EDL in the presence of an external transmembrane electric field are yet to be characterized.
Yao Yao +3 more
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Selective (Bio)Functionalization of Solid-State Nanopores
ACS Applied Materials & Interfaces, 2015We present a method to selectively (bio)functionalize nanoscale features with the same materials chemistry. It was successfully combined with nanosphere lithography to fabricate and functionalize solid-state nanopores with PEG-brushes, supported lipid membranes, and functional proteins over large areas.
Pla-Roca Mateu +3 more
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Solid-state nanopores for biosensing with submolecular resolution
Biochemical Society Transactions, 2012Biological cell membranes contain various types of ion channels and transmembrane pores in the 1–100 nm range, which are vital for cellular function. Individual channels can be probed electrically, as demonstrated by Neher and Sakmann in 1976 using the patch-clamp technique [Neher and Sakmann (1976) Nature 260, 799–802].
Japrung, Deanpen +3 more
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Dynamics of Colloids in Single Solid-State Nanopores
The Journal of Physical Chemistry B, 2011We use solid-state nanopores to study the dynamics of single electrically charged colloids through nanopores as a function of applied voltage. We show that the presence of a single colloid inside of the pore changes the pore resistance, in agreement with theory.
Bacri, Laurent +7 more
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DNA-functionalized solid state nanopore for biosensing
Nanotechnology, 2010The possible use of nanopores for single DNA molecules biosensing has been demonstrated, but much remains to do in order to develop advanced engineered devices with enhanced stability, and controlled geometry and surface properties. Here we present morphological and electrical characterization of solid state silicon nitride nanopores fabricated by ...
MUSSI, VALENTINA +7 more
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