The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]
, 2011 Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E +20 more
core +2 more sources
Molecular Therapy: Nucleic Acids, 2016 The androgen receptor plays a critical role in the progression of prostate cancer. Here, we describe targeting the prostate-specific membrane antigen using a lipid nanoparticle formulation containing small interfering RNA designed to silence expression ...
Justin B Lee +13 more
doaj +1 more source
Hypolipidemic and Hepatoprotective Effects of Myricitrin and Solid Lipid Nanoparticle-containing Myricitrin on the Male Mouse Model with Type 2 Diabetes Induced by Streptozotocin-Nicotinamide [PDF]
Journal of Kerman University of Medical Sciences, 2021 Background: Type 2 diabetes mellitus (T2DM) has several complications such as hyperlipidemia and hepatotoxicity. Myricitrin has an antidiabetic action along with low bioavailability.
Akram Ahangarpour +4 more
doaj +1 more source
A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption [PDF]
, 2012 Purpose. Drug release from nanosystems at the sites of either absorption or effect biophase is a major determinant of its biological action. Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo ...
Adibkia, Khosro +6 more
core +3 more sources
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin [PDF]
, 2020 Riboflavin (RF) is a water-soluble member of the B-vitamin family. Sufficient dietary and supplemental RF intake appears to have a protective effect on various medical conditions such as sepsis, ischemia etc., while it also contributes to the reduction ...
Bäumler, Hans +4 more
core +1 more source
Multimodal Magnetic Resonance and Near-Infrared-Fluorescent Imaging of Intraperitoneal Ovarian Cancer Using a Dual-Mode-Dual-Gadolinium Liposomal Contrast Agent. [PDF]
, 2016 The degree of tumor removal at surgery is a major factor in predicting outcome for ovarian cancer. A single multimodality agent that can be used with magnetic resonance (MR) for staging and pre-surgical planning, and with optical imaging to aid surgical ...
Annapragada, A +7 more
core +2 more sources
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
, 2020 Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core +1 more source
Xylem surfactants introduce a new element to the cohesion-tension theory [PDF]
, 2016 Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under ...
Do, Aissa YT +10 more
core +1 more source
Solid lipid nanoparticles loading with curcumin and dexanabinol to treat major depressive disorder
Neural Regeneration Research, 2021 Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative that exerts neuroprotective effects through anti-inflammatory and antioxidant effects. Curcumin exhibits antidepressant effects in the treatment of major depressive disorder.
Xiao-Lie He +5 more
doaj +1 more source