Results 331 to 340 of about 1,859,179 (392)

Solid-Phase Synthesis of Isoxazolines

Journal of Combinatorial Chemistry, 2002
The polymer-supported synthesis of isoxazolines is described via nitrile oxide intermediates, starting from primary nitroalkanes in a one-pot process.
S, Chandrasekhar, Abbas, Raza, M Venkat, Reddy, J S, Yadav   +3 more
openaire   +2 more sources

Solid-Phase Synthesis of Phosphopeptides

2013
Phosphopeptides are generally prepared by incorporation of suitable, protected phosphoamino acid derivatives during peptide synthesis using routine coupling protocols. The feasibility of chemical synthesis of phosphorylated peptides by Fmoc-SPPS was greatly enhanced by the introduction of the monobenzyl protecting group for the phosphate group.
Højlys-Larsen, Kim B., Jensen, Knud Jørgen   +1 more
openaire   +3 more sources

Solid-Phase Synthesis of CD40L Mimetics

Synfacts, 2006
The C3-symmetric molecule has been previously shown to mimic CD40 ligand (CD40L) homotrimers and to display effector functions. This molecule consists of a cyclic hexapeptide core containing the repetition of the D-Ala-L-Lys motif. The side chains of the lysine residues have been modified by appending the CD40L-derived sequence 143Lys-Gly-Tyr-Tyr146 ...
Alberto, Bianco, Sylvie, Fournel, Sébastien, Wieckowski, Johan, Hoebeke, Gilles, Guichard   +4 more
openaire   +2 more sources

Grafted supports in solid-phase synthesis

Biopolymers, 2000
Solid-phase synthesis is greatly dependent on the solid phase. We are interested in the development of a "pellicular" type of solid support where a more mobile polymer is grafted to rigid plastics. Compared to low cross-linked microporous beads that dominate the field, this approach allows great flexibility of design, as plastics are available as ...
Rasoul, Firas, Ercole, Francesca, Pham, Yen, Bui, Chinh T., Wu, Zemin, James, Susan N., Trainor, Robert W., Wickham, Geoffrey, Maeji, N. Joe   +8 more
openaire   +2 more sources

Automated Solid-Phase Synthesis of Oligosaccharides

Science, 2001
Traditionally, access to structurally defined complex carbohydrates has been very laborious. Although recent advancements in solid-phase synthesis have made the construction of complex oligosaccharides less tedious, a high level of technical expertise is still necessary to obtain the desired structures.
Plante, O., Palmacci, E., Seeberger, P.
openaire   +3 more sources

Automated Solid-Phase Peptide Synthesis

2019
The development of solid-phase peptide synthesis by Bruce Merrifield paved the way for a synthesis carried out by machines. Automated peptide synthesis is a fast and convenient way of synthesizing many peptides simultaneously. This chapter tries to give a general guidance for the development of synthesis protocols for the peptide synthesizer.
openaire   +2 more sources

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides.

Analytical Biochemistry, 1970
E. Kaiser, R. Colescott, C. D. Bossinger, P. I. Cook   +3 more
semanticscholar   +1 more source

Solid phase peptide synthesis. I. the synthesis of a tetrapeptide

, 1963
R. B. Merrifield
semanticscholar   +1 more source

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.

International journal of peptide & protein research, 2009
G. Fields, R. Noble
semanticscholar   +1 more source

Solid phase synthesis

Journal of Chemical Education, 1975
openaire   +3 more sources