Results 81 to 90 of about 424,559 (254)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Spin density encodes intramolecular singlet exciton fission in pentacene dimers

Nature Communications, 2019
Singlet exciton fission – the separation of photoexcited singlet states into two triplet states – holds promise for enhancing photocurrents in photovoltaic technologies. Krishnapriya et al.
K. C. Krishnapriya, Palas Roy, Boregowda Puttaraju, Ulrike Salzner, Andrew J. Musser, Manish Jain, Jyotishman Dasgupta, Satish Patil   +7 more
doaj   +1 more source

cis-[3-(2-Chloro-6-methylquinolin-3-yl)oxiran-2-yl](p-tolyl)methanone

IUCrData, 2017
In the title compound, C20H16ClNO2, the dihedral angle between the quinolyl ring system and the p-tolyl ring is 65.80 (7)°. The rings are bridged by a functionalized epoxide system, with the exocyclic bonds in a cis configuration.
Narasimhamurthy Preveena, Amar A. Hosamani, Managutti Praveen, Gopalpur Nagendrappa, Tayur N. Guru Row   +4 more
doaj   +1 more source

Structure and electronic structure of Metal-Organic Frameworks within the Density-Functional based Tight-Binding method

, 2011
Density-functional based tight-binding is a powerful method to describe large molecules and materials. Metal-Organic Frameworks (MOFs), materials with interesting catalytic properties and with very large surface areas have been developed and have become ...
Frenzel, Johannes, Heine, Thomas, Kuc, Agnieszka B., Lukose, Binit, Petkov, Petko St., Seifert, Gotthard, Supronowicz, Barbara, Vayssilov, Georgi N.   +7 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Bases of inorganic and organic chemistry [PDF]

, 2016
Stated fundamental theoretical principles of general, inorganic and organic chemistry and analyzed the reactivity of the most important classes of inorganic and organic substances. A multivariate tasks and exercises for classroom and independent work are
Alami, D., Slavkova, M., Ved, M.
core  

Virtual-crystal approximation that works: Locating a composition phase boundary in Pb(Zr_{1-x}Ti_3)O_3

, 2000
We present a new method for modeling disordered solid solutions, based on the virtual crystal approximation (VCA). The VCA is a tractable way of studying configurationally disordered systems; traditionally, the potentials which represent atoms of two or ...
A. M. Glazer, A. M. Rappe, Andrew M. Rappe, B. Jaffe, B. Jaffe, C. Chen, C. Froese, C. Michel, D. A. Papaconstantopoulos, D. Vanderbilt, F. J. Pinski, G. M. Stocks, H. J. Monkhorst, J. S. Faulkner, J. S. Faulkner, J. S. Faulkner, L. Bellaiche, L. Bellaiche, L. Kleinman, L. Nørdheim, N. J. Ramer, N. J. Ramer, N. J. Ramer, N. Marzari, Nicholas J. Ramer, P. Slavenburg, P. Soven, P. Soven, R. Clarke, S. de Gironcoli, T. Muto   +30 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Structural and physical properties of layered oxy-arsenides LnRuAsO (Ln = La, Nd, Sm, Gd)

, 2012
Polycrystalline samples of LaRuAsO, NdRuAsO, SmRuAsO, and GdRuAsO have been synthesized and studied using powder x-ray diffraction, electrical transport, magnetization, and heat capacity measurements. Variations in structural properties across the series
Aeby, Andrew F. May, Barker, Brian C. Sales, Chen, Cimberle, Cui, Jetischko, Johnston, Kamihara, Kreyssig, McGuire, McGuire, Michael A. McGuire, Nath, Nitsche, Pal, Pallecchi, Quebe, Rodriguez-Carvajal, Schnelle, Sefat, Shannon, Sharma, Tropeano, Wang, Zhao   +26 more
core   +1 more source