Results 91 to 100 of about 619,940 (356)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
DESIGN AND OPERATION OF A SOLID-STATE TRANSFORMER FOR INTEGRATION OF RENEWABLE ENERGY SYSTEMS
Taikomieji tyrimai studijose ir praktikoje, 2020 Renewable energy-based grid integrations in distribution systems cause changes in the energy structure of the grid such as load flow, short circuit and protection coordination.
Burak Esenboğa +2 more
doaj
A Hierarchical Coordinative Control Strategy for Solid State Transformer Based DC Microgrids
Applied Sciences, 2020 A solid state transformer (SST), as a kind of energy router in the Energy Internet, provides a unified access point for AC or DC distributed power subjects.
Zheng Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Testing collapse models with levitated nanoparticles: the detection challenge [PDF]
, 2019 We consider a nanoparticle levitated in a Paul trap in ultrahigh cryogenic vacuum, and look for the conditions which allow for a stringent noninterferometric test of spontaneous collapse models.
Barker, P. F. +5 more
core +2 more sources
Mechanochemically Induced Solid-State Transformations of Levofloxacin
Molecular PharmaceuticsLevofloxacin hemihydrate (LVXh) is a complex fluoroquinolone drug that exists in both hydrated and anhydrous/ dehydrated forms. Due to the complexity of such a compound, the primary aim of this study was to investigate the amorphization capabilities and solid-state transformations of LVXh when exposed to mechanical treatment using ball milling.
Lena Kadri +4 more
openaire +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
EnergiesThis study presents a novel structure proposal of a variable inductance high-frequency transformer for enhancement power level of a dual-active-bridge (DAB) converter.
Cheol-Woong Choi +5 more
doaj +1 more source
Modeling and Stability Analysis of a Smart Transformer-Fed Grid
IEEE Access, 2020 The interaction of the smart transformer (ST) with the grid-converter-based distributed energy resources (DERs) could trigger instability. Recent research efforts have been made to study the stability issues caused by the resonances (e.g.
Zhixiang Zou +3 more
doaj +1 more source